CPN1 (NM_001308) Human Untagged Clone

CAT#: SC125560

CPN1 (untagged)-Human carboxypeptidase N, polypeptide 1 (CPN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CPN1
• Synonyms: CPN; SCPN
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001308, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAGACCTGCTCTCAGTCTTCCTCCACCTCCTCCTTCTCTTCAAGTTGGTTGCCCCGGTGACCTTTC
  GCCACCACCGCTATGATGATCTTGTGCGGACGCTGTACAAGGTGCAAAACGAATGCCCCGGCATCACGCG
  GGTCTACAGCATTGGGCGCAGCGTGGAGGGGAGACACCTCTACGTGCTGGAGTTCAGCGACCACCCTGGA
  ATCCACGAGCCCTTGGAACCAGAGGTCAAGTATGTGGGGAACATGCACGGCAACGAAGCGTTGGGCCGCG
  AGCTGATGCTGCAGCTGTCGGAGTTTCTGTGCGAGGAGTTCCGGAACAGGAACCAGCGCATCGTCCAGCT
  CATCCAGGACACGCGCATTCACATCCTGCCATCCATGAACCCCGACGGCTACGAGGTGGCTGCTGCCCAG
  GGCCCAAACAAGCCTGGGTATCTAGTTGGCAGGAACAATGCAAATGGAGTGGACCTGAACCGCAACTTCC
  CTGATCTCAATACCTATATCTACTATAACGAGAAGTACGGAGGCCCCAACCACCACCTGCCCCTTCCAGA
  CAACTGGAAAAGTCAGGTGGAACCCGAGACCCGGGCGGTGATCCGGTGGATGCACTCCTTCAACTTTGTT
  CTTTCAGCCAATCTCCACGGAGGGGCGGTGGTGGCCAATTACCCGTATGACAAGTCCTTTGAGCACCGGG
  TCCGAGGGGTCCGCCGCACCGCCAGCACCCCCACGCCTGACGACAAGCTCTTCCAGAAGCTGGCCAAGGT
  CTACTCCTATGCACATGGATGGATGTTCCAAGGTTGGAACTGCGGAGATTACTTCCCAGATGGCATCACC
  AATGGGGCTTCCTGGTATTCTCTCAGCAAGGGAATGCAAGACTTTAATTATCTCCATACCAACTGCTTTG
  AGATCACGCTGGAACTGAGTTGCGACAAGTTTCCCCCCGAAGAGGAGTTACAGCGGGAGTGGCTGGGTAA
  TCGGGAAGCCCTAATCCAGTTCCTGGAACAGGTTCACCAGGGCATCAAGGGAATGGTGCTTGATGAGAAT
  TACAATAATCTCGCCAATGCTGTCATTTCTGTCAGTGGGATTAACCATGATGTCACTTCAGGTGACCATG
  GTGATTACTTCCGGCTGCTGCTTCCAGGTATCTACACTGTTAGTGCCACAGCACCTGGGTATGACCCAGA
  GACAGTAACTGTGACCGTGGGTCCTGCGGAACCAACGTTGGTTAACTTCCACCTCAAAAGAAGCATCCCT
  CAAGTAAGCCCTGTGAGGAGAGCTCCCAGCAGAAGGCACGGAGTCAGAGCCAAAGTGCAGCCCCAAGCCA
  GAAAGAAAGAAATGGAGATGAGGCAGCTGCAGAGAGGCCCTGCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001308 unedited
  NNNNNGGTCGNAATTTGTATACGACTCATATAGGGCGGCCGCGATTCAGATCTGGTANCC
  GGTCCGGAATTCCCGGGATTGCAAAAAACCTTTCAAAAGCTTTCCTGGATTAGAGAAAGA
  AAGGGAGTGAGGGAGGAGAGATGAGTGGCTATTCCAGAACGACATAAAGAATTTCCAGCC
  TTGGACGGACAGCTGGGAACGTCTTCCAATTTGGACTGGTGTTTACAAGCGGGAAGCTAG
  GTGGACCTTGGATTTTGGCGGGTGAAGAGGCTAGGTTGTTTAAGGAGGTGGGGCGCGTTT
  CAGTGGCTCTCTTTGAAAAAGCCCAGCAAGATGTCAGACCTGCTCTCAGTCTTCCTCCAC
  CTCCTCCTTCTCTTCAAGTTGGTTGCCCCGGTGACCTTTCGCCACCACCGCTATGATGAT
  CTTGTGCGGACGCTGTACAAGGTGCAAAACGAATGCCCCGGCATCACGCGGGTCTACAGC
  ATTGGGCGCAGCGTGGAGGGGAGACACCTCTACGTGCTGGAGTTCAGCGACCACCCTGGA
  ATCCACGAGCCCTTGGAACCAGAGGTCAAGTATGTGGGGAACATGCACGGCAACGAAGCG
  TTGGGCCGCGAGCTGATGCTGCAGCTGTCGGAGTTTCTGTGCGAGGAGTTCCGGAACAGG
  AACCAGCGCATCGTCCAGCTCATCCAGGACACGCGCATTCACATCCTGCCATCCATGAAC
  CCCGACNGCTACGAGGTGGCTGCTGCCCAGGGCCCAAACAAGCCTGGGTATCTAGTTGGC
  AGGAACAATGCANATGGAGTGGACCTGAACCCGCACTTCCCTGATCTCATACCTATATCT
  ACTATAACGAGAAGTACGGGAGGCCCCAACACCACCTGCCCCTTTCAGACACTGGNAAAG
  NNTCAGTGGACCCGAAC
  
• Restriction Sites: Please inquire
• ACCN: NM_001308
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001308.1, NP_001299.1
• RefSeq Size: 1756 bp
• RefSeq ORF: 1377 bp
• Locus ID: 1369
• Cytogenetics: 10q24.2
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: 'Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]'