PHOX2A (NM_005169) Human Untagged Clone

CAT#: SC126005

PHOX2A (untagged)-Human paired-like homeobox 2a (PHOX2A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PHOX2A
• Synonyms: ARIX; CFEOM2; FEOM2; NCAM2; PMX2A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005169 edited
  CTGAGTGCGGCCGCGACGGGGCGGGCGGACTCTCGGGCGCTCAGAGCTGGCCTCGGGTCC
  TCGGAGCCTGGCGCTCGAACCTCCCTTCCGACCTCCACCCGGACCCCGACCCCGACCCGG
  CCTGGCCCGGCCCCCGCCCCCGCCCCCCGGGCCGATGGACTACTCCTACCTCAATTCGTA
  CGACTCGTGCGTGGCGGCCATGGAGGCGTCCGCCTACGGCGACTTTGGCGCCTGCAGCCA
  GCCCGGCGGCTTCCAATACAGCCCCCTGCGGCCCGCTTTCCCCGCGGCAGGGCCGCCCTG
  CCCCGCGCTCGGCTCCTCCAACTGCGCACTTGGCGCCCTACGCGACCACCAGCCCGCGCC
  CTACTCGGCAGTGCCCTACAAGTTCTTCCCAGAGCCATCCGGCCTGCACGAGAAGCGCAA
  GCAGCGGCGCATCCGCACCACGTTCACCAGCGCGCAGCTCAAGGAGCTGGAGCGCGTTTT
  CGCTGAGACCCACTACCCCGACATTTACACGCGTGAGGAGCTGGCGCTCAAGATCGACCT
  CACTGAGGCTCGCGTGCAGGTCTGGTTCCAGAACCGCCGGGCCAAGTTCCGCAAACAGGA
  GCGCGCGGCCAGCGCCAAGGGCGCGGCGGGCGCGGCGGGCGCCAAAAAGGGCGAGGCGCG
  CTGCTCCTCCGAGGACGACGATTCCAAGGAGTCCACGTGCAGCCCCACGCCCGATAGCAC
  CGCCTCGCTGCCGCCGCCGCCTGCGCCCGGCCTGGCCAGCCCGCGCCTGAGCCCCAGCCC
  GCTGCCCGTCGCACTGGGCTCCGGGCCGGGACCTGGGCCGGGGCCACAGCCGCTCAAGGG
  CGCACTGTGGGCCGGTGTGGCGGGCGGTGGGGGCGGCGGGCCTGGCGCGGGAGCGGCCGA
  ACTACTTAAGGCTTGGCAGCCGGCGGAGTCCGGCCCCGGGCCCTTCTCCGGGGTTCTGTC
  CTCCTTTCACCGGAAGCCCGGCCCCGCCCTGAAGACCAATCTCTTCTAGCTGCCGGCCTC
  TGGAGGCTCCGAGCCTGCCCCCAGAGACGTCCCTGCCCCTCCAGGACCTGACAGCCCCTC
  CCATCCTGGCCACCCGCCTGGAAGTCCCCATCCGTCTCCACTCCCTACTGTCTCACCCCT
  CGGTGTGTCCTCCCCAACTTTGGAGACCAAGTCAGGGCCACTCTCGTCCTCACCCACCCT
  CTACCAGCAGAGCGGAGTTCTTTATACCGGGACCTCCTCCAGGAGAACCCCGGAGCTCCT
  TCTAGCTTGGCCTTCTTTGGATGCGGTATCACATGAGGCCTGTCCCTAACAGTGCCCTCA
  AAGTGAAGGTCCTCAAGGAGGATCGGCACAGCCCCCTTCCCTGGCTCTGCAGCGGCTGGG
  TCACCCCTTACGCTGGTGATCAGGAAAGCCCGCTGCCCCACCCCTCGGGCCCACCCGTAC
  AGAGGCTGGTGGTCGCCGGGATAATTAATGACCACCGCCAATTCATCCCTCACGTGTCTC
  CTCTCTTCCCTAGCCCGTCTGGCACAGAGGGTGGACCTGTTAGAGGAGTGGAGGGGCTGC
  CTGGGGAATGGGACAGAGGGATTCTCTTTCCCTAATTTTTTTGGTTGTCCTTTTTCTTTG
  AAAAACTTGTAATTTATTGAAGTTTTACTCAATCCAAATAAAACTTAATTTATTGAAGAC
  AAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005169 unedited
  GTTCAGGATTTGTAAACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGAGTGCG
  GCCGCGACGGGGCGGGCGGACTCTCGGGCGCTCAGAGCTGGCCTCGGGTCCTCGGAGCCT
  GGCGCTCGAACCTCCCTTCCGACCTCCACCCGGACCCCGACCCCGACCCGGCCTGGCCCG
  GCCCCCGCCCCCGCCCCCCGGGCCGATGGACTACTCCTACCTCAATTCGTACGACTCGTG
  CGTGGCGGCCATGGAGGCGTCCGCCTACGGCGACTTTGGCGCCTGCAGCCAGCCCGGCGG
  CTTCCAATACAGCCCCCTGCGGCCCGCTTTCCCCGCGGCAGGGCCGCCCTGCCCCGCGCT
  CGGCTCCTCCAACTGCGCACTTGGCGCCCTACGCGACCACCAGCCCGCGCCCTACTCGGC
  AGTGCCCTACAAGTTCTTCCCAGAGCCATCCGGCCTGCACGAGAAGCGCAAGCAGCGGCG
  CATCCGCACCACGTTCACCAGCGCGCAGCTCAAGGAGCTGGAGCGCGTTTTCGCTGAGAC
  CCACTACCCCGACATTTACACGCGTGAGGAGCTGGCGCTCAAGATCGACCTCACTGAGGC
  TCGCGTGCAGGTCTGGTTCCAGAACCGCCGGGCCAAGTTCCGCANACAGGAGCGCGCGGC
  CAGCGCCAAGGGCGCGGCGGGCGCGGCGGGCGCCAAAAGGGCGAGGCGCGCTGCTCCTCC
  GAGGACGACGATTCCAAGGAGTCCACGTGCAGCCCCACGCCCGATAGCACCGCCTCGCTG
  CCGCCGCCGCCTGCGCCCGGCCTGGCCAGCCCGCGCCTGAGCCCCAGCCCGCTGCCCGTC
  GCACTGGGCTCCGGGCCGGGACCTGNGCCCGGGCCACAGCCGCTCAGGGCGCACTGTGGG
  CCCGTGTGGCGGGCGGTGGGGGCGGCCGGCCTTGCGCCGGGACCGCCN
  
• Restriction Sites: Please inquire
• ACCN: NM_005169
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005169.2, NP_005160.2
• RefSeq Size: 1700 bp
• RefSeq ORF: 855 bp
• Locus ID: 401
• Cytogenetics: 11q13.4
• Protein Families: Transcription Factors
• Gene Summary: 'The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]'