FMO2 (NM_001460) Human Untagged Clone

CAT#: SC126279

FMO2 (untagged)-Human flavin containing monooxygenase 2 (non-functional) (FMO2)


  "NM_001460" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol FMO2
Synonyms FMO1B1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001460 edited
ACAACCAAGGGAGAAAACTATTCTGTCAAAGAGACGGTGCCAAAAGGCAAAAACAAAGGA
GCTGATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAA
GTGCTGTGTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTGGAGG
AGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCGT
TACCAACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTCC
AAACTTCCTGCATAATTCTAAACTTCTGGAATATTTCAGGATTTTTGCTAAAAAATTTGA
TCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATTT
CTCATCCTCTGGCCAATGGAAGGTTGTCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGT
CTTTGACGCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGAAGTC
ATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATCC
AGATGGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCAGGCTCAGATAT
TGCTGTTGAGCTGAGTAAGAATGCTGCTCAGGTTTTTATCAGCACCAGGCATGGCACCTG
GGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTT
TCGTTCTATGCTCCGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACA
GATGAATCGGTGGTTCAACCATGAAAATTATGGCCTTGAGCCTCAAAACAAATACATTAT
GAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGTCTACTCTGTGGAGCCATCAAGGT
GAAATCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATCTTTGAGGATGGAACAGTGGA
GGAGAACATTGATGTCATCATTTTTGCAACAGGATATAGTTTCTCTTTTCCCTTCCTTGA
AGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCCGC
TCACCTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTT
CCCAACTGCTGAACTTCAAGCTCGTTGGGTGACAAGAGTTTTCAAAGGCTTGTGTAGCCT
GCCCTCAGAGAGAACTATGATGATGGACATTATCAAAAGGAATGAAAAAAGAATTGACCT
GTTTGGAGAAAGCCAGAGCCAGACGTTGCAGACCAATTATGTTGACTACTTGGACGAGCT
CGCCTTAGAGATAGGTGCGAAGCCAGATTTCTGCTCTCTCTTGTTCAAAGATCCTAAACT
GGCTGTGAGACTCTATTTCGGACCCTGCAACTCCTATTAGTATCGCCTGGTTGGGCCTGG
GCAATGGGAAGGAGCCAGAAATGCCATCTTCACCCAGAAACAAAGAATACTGAAGCCACT
CAAGACTCGGGCCCTGAAGGATTCATCTAATTTCTCAGTTTCTTTTCTGTTGAAAATCCT
GGGCCTTCTTGCTGTTGTTGTGGCCTTTTTTTGCCAACTTCAATGGTCCTAGTCAGCATA
ATGCTTTGGGCTTTATTATCTTGTCAGTCACTACCTCCTAAAAAAAAAAAAAAAAAAAAA
AAAAAAA
>OriGene 5' read for NM_001460 unedited
GTTCAGGAATTTGTAATACGACTCCACTATAGGCGGCCGCGCAATTCGCCATTACGGCCG
GGGACAACCAAGGAGAAAACTATTGTGTCAAAGAACGGTGCCAAAAGGCAAAAACAAAGG
AGCTGATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGA
AGTGCTGTGTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTGGAG
GAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCG
TTACCAACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTC
CAAACTTCCTGCATAATTCTAAACTTCTGGAATATTTCAGGAGTTTTGCTAAAAAATTTG
ATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATT
TCTCATCCTCTGGCCAATGGAAGGTTGTCACTCAAAGCAACGGCAAGGAGCAGAGTGCTG
TCTTTGACGCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGAAGT
CATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATC
CAGATGGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCANGCTCANATA
TTGCTGTTGAGCTGAGTAAGAATGCTGCTCANGTGTTTATCAGCACCAGCATGGCACCTG
GGTCATGAGCCCTATCTCTGAGATGGCTATCCTTGGGACTCANTGTTCCACACCGGTTTC
GTTCATGCTCCGCATGTACTGCCACAACAGCTGTAAAATGGTGATAGGACAACGATGAAT
CGTTGGTCAACCTGAAAATATGGGCCTTAGCCTCAAACAATACTTATGA
Restriction Sites Please inquire     
ACCN NM_001460
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001460.2, NP_001451.1
RefSeq Size 5181 bp
RefSeq ORF 1416 bp
Locus ID 2327
Cytogenetics 1q24.3
Protein Pathways Drug metabolism - cytochrome P450
Gene Summary 'This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]'
Transcript Variant: This variant (1), which represents the functional FMO2*1 allele, is the longer transcript and encodes the longer isoform (a).

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