FMO2 (NM_001460) Human Untagged Clone

CAT#: SC126279

FMO2 (untagged)-Human flavin containing monooxygenase 2 (non-functional) (FMO2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FMO2
• Synonyms: FMO1B1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001460 edited
  ACAACCAAGGGAGAAAACTATTCTGTCAAAGAGACGGTGCCAAAAGGCAAAAACAAAGGA
  GCTGATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAA
  GTGCTGTGTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTGGAGG
  AGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCGT
  TACCAACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTCC
  AAACTTCCTGCATAATTCTAAACTTCTGGAATATTTCAGGATTTTTGCTAAAAAATTTGA
  TCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATTT
  CTCATCCTCTGGCCAATGGAAGGTTGTCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGT
  CTTTGACGCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGAAGTC
  ATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATCC
  AGATGGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCAGGCTCAGATAT
  TGCTGTTGAGCTGAGTAAGAATGCTGCTCAGGTTTTTATCAGCACCAGGCATGGCACCTG
  GGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTT
  TCGTTCTATGCTCCGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACA
  GATGAATCGGTGGTTCAACCATGAAAATTATGGCCTTGAGCCTCAAAACAAATACATTAT
  GAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGTCTACTCTGTGGAGCCATCAAGGT
  GAAATCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATCTTTGAGGATGGAACAGTGGA
  GGAGAACATTGATGTCATCATTTTTGCAACAGGATATAGTTTCTCTTTTCCCTTCCTTGA
  AGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCCGC
  TCACCTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTT
  CCCAACTGCTGAACTTCAAGCTCGTTGGGTGACAAGAGTTTTCAAAGGCTTGTGTAGCCT
  GCCCTCAGAGAGAACTATGATGATGGACATTATCAAAAGGAATGAAAAAAGAATTGACCT
  GTTTGGAGAAAGCCAGAGCCAGACGTTGCAGACCAATTATGTTGACTACTTGGACGAGCT
  CGCCTTAGAGATAGGTGCGAAGCCAGATTTCTGCTCTCTCTTGTTCAAAGATCCTAAACT
  GGCTGTGAGACTCTATTTCGGACCCTGCAACTCCTATTAGTATCGCCTGGTTGGGCCTGG
  GCAATGGGAAGGAGCCAGAAATGCCATCTTCACCCAGAAACAAAGAATACTGAAGCCACT
  CAAGACTCGGGCCCTGAAGGATTCATCTAATTTCTCAGTTTCTTTTCTGTTGAAAATCCT
  GGGCCTTCTTGCTGTTGTTGTGGCCTTTTTTTGCCAACTTCAATGGTCCTAGTCAGCATA
  ATGCTTTGGGCTTTATTATCTTGTCAGTCACTACCTCCTAAAAAAAAAAAAAAAAAAAAA
  AAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001460 unedited
  GTTCAGGAATTTGTAATACGACTCCACTATAGGCGGCCGCGCAATTCGCCATTACGGCCG
  GGGACAACCAAGGAGAAAACTATTGTGTCAAAGAACGGTGCCAAAAGGCAAAAACAAAGG
  AGCTGATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGA
  AGTGCTGTGTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTGGAG
  GAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCG
  TTACCAACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTC
  CAAACTTCCTGCATAATTCTAAACTTCTGGAATATTTCAGGAGTTTTGCTAAAAAATTTG
  ATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATT
  TCTCATCCTCTGGCCAATGGAAGGTTGTCACTCAAAGCAACGGCAAGGAGCAGAGTGCTG
  TCTTTGACGCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGAAGT
  CATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATC
  CAGATGGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCANGCTCANATA
  TTGCTGTTGAGCTGAGTAAGAATGCTGCTCANGTGTTTATCAGCACCAGCATGGCACCTG
  GGTCATGAGCCCTATCTCTGAGATGGCTATCCTTGGGACTCANTGTTCCACACCGGTTTC
  GTTCATGCTCCGCATGTACTGCCACAACAGCTGTAAAATGGTGATAGGACAACGATGAAT
  CGTTGGTCAACCTGAAAATATGGGCCTTAGCCTCAAACAATACTTATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001460
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001460.2, NP_001451.1
• RefSeq Size: 5181 bp
• RefSeq ORF: 1416 bp
• Locus ID: 2327
• Cytogenetics: 1q24.3
• Protein Pathways: Drug metabolism - cytochrome P450
• Gene Summary: 'This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]'
  Transcript Variant: This variant (1), which represents the functional FMO2*1 allele, is the longer transcript and encodes the longer isoform (a).