RDHE2 (SDR16C5) (NM_138969) Human Untagged Clone

CAT#: SC126363

SDR16C5 (untagged)-Human short chain dehydrogenase/reductase family 16C, member 5 (SDR16C5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SDR16C5
• Synonyms: EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138969 edited
  CCGGCTTCTCCGCGGACAGCTAGGGAGAGTGTCCTGGGTGTCAGCCAGAACATGTCTTTC
  AACCTGCAATCATCAAAGAAACTGTTCATTTTCTTAGGAAAATCACTGTTTAGTCTTCTG
  GAGGCTATGATTTTTGCCTTACTCCCAAAGCCACGGAAGAACGTTGCTGGTGAAATAGTC
  CTCATCACAGGTGCTGGAAGTGGACTCGGAAGGCTCTTAGCCTTGCAGTTTGCCCGGCTG
  GGATCTGTTCTTGTTCTCTGGGATATCAATAAGGAGGGGAATGAGGAAACATGTAAGATG
  GCTCGGGAAGCTGGAGCCACAAGAGTGCACGCCTATACCTGCGATTGCAGCCAAAAGGAA
  GGAGTGTATAGAGTAGCCGACCAGGTTAAAAAAGAAGTCGGCGATGTTTCCATCCTAATC
  AACAATGCCGGAATCGTAACAGGCAAAAAGTTCCTTGACTGTCCAGATGAGCTTATGGAA
  AAGTCATTTGATGTGAATTTCAAAGCACATTTATGGACTTATAAAGCCTTTCTACCTGCT
  ATGATTGCTAATGACCATGGACATTTGGTTTGCATTTCAAGTTCAGCTGGATTAAGTGGA
  GTAAATGGGCTGGCAGATTACTGTGCAAGTAAATTTGCAGCCTTTGGGTTTGCTGAATCT
  GTATTTGTAGAAACATTTGTCCAAAAACAAAAGGGGATCAAAACCACGATTGTGTGCCCC
  TTTTTTATAAAAACTGGAATGTTTGAAGGTTGTACTACAGGCTGTCCTTCTCTGTTGCCA
  ATTCTGGAACCAAAATATGCAGTTGAAAAAATAGTAGAAGCTATTCTACAAGAAAAAATG
  TACTTGTATATGCCAAAGTTGTTATACTTCATGATGTTTCTTAAAAGCTTTTTGCCCCTC
  AAGACAGGACTGCTTATAGCTGACTATTTGGGCATCCTTCATGCAATGGATGGCTTTGTT
  GACCAAAAGAAGAAGCTCTAAAGACCAACTCTATGGCTAAGGTCATCTGATACACAGTGT
  TACATAATGCGTACTTCAATGAAGAAAAGTATTTTTGTCTGACAGTGGAATATATCTGGA
  GACCACAAGTACCACTCCTATTCTGTTATCTGGACTAGAATTTTCAATCAATGTGTTTGA
  AAATAATGTTGCTATCACCTATTTGGTTGAGTTTTGGTTTTTTCTTTTTCTTTTTTTTTC
  CAAAAATAAAGACAGCCCATTTTTGTCATTTCCATTACCACAGATGTAAGAAAGTGATAA
  GCCATGGCCATGAGCTGCCCTGAGCTTTGGTCGTTGGGGAGGTGGCTCAAATGGAGCCAG
  CGGCTGTGGTTGACCTGCCTTGGGGAGCAGGGCTGAGGGGCGAAGAGGACATGTGGATAT
  CCAGCCAGAATGCCCTCTCTCCAGAGGACACACAGCTCTGGATTTCTACCCCCTTGCTAT
  CCTCTCTGGCCATTTTGAACCTGTACCACCTAATGTAGAAAAGGCCCGCCTCCAGTGCCC
  TTCTTTCCAAAACAGCTACACAAATGCTTCTGAATGCCCTGGATACGCAGACCGAGTGGC
  AGTCTGGCTAAAGGCCCATCCAGCACTATTGTGCCCAAGAGCCTTACCGGGCATTCCCTG
  AAGCCCCCTCATAGGCAGTGATCCTAGACCAAACTCTTAAATAGAATCACTTTTGTTTCC
  TAGAAGAGATCAAAGAGTGGTTGCTTCTTACTTTGAAGATGAAATTATACCAAGTTAGGT
  TTTTTGCTATCTATTGATCCAAAAAATATATTCGTGCAATTAAAGTTAAGTGTTCAACTT
  AGTATTTCAAGTTGGGATTCAGGTTGAGGCATTTTCCTGCAGAATGGGCAATTTTATGCA
  TTTATATTCATCAGTGCTGCCCTCACTTTGGATCTATTGTATTCTTACAGTTTAATCAAC
  TGGCAAAGTGCTTTCATGCTTTGGAGATTAACTATAAAAGCAAGATTAAGAAAAATATGT
  TAATTACCATATCCCTGGAACTCCTTCTCAGGCTGGTGGGGGCAGCCTTGCAAGAGAAAC
  AGCAGCCTTTGTCTCTTCCCTCTTGTGGGGAGCAAGGAGGGGATGAGCGGTACCTTGGGA
  GACCCGGTAAAAGTCTAAAGAATTGAGAATTTGACTATCTTGGGGGTAAAATGCTGTCAT
  AGGGGCAGCAGTCTCAGGGGGTGTAAACTCTGGAATCCACTATGGTTTACCTTGAGTGGC
  CTGCACGAACATGACAGCCCTGATCTGTATTTCCTTTCCATTCAGAAAACCTTAAAAAAA
  AAAAACTTGTTTTATGATAATATTATAACAATCATAACTAACATTTACTGTGCCCGGCAG
  CAAATTAAGTATTTGACAAACATTATTTCATTAAACGAGACTGTCAATCATTACTCAAAG
  AATGATGAAGGTATTTGGTGTATGCCAAAGAATAAAGGCGTTTTATTTCACAGTGACATC
  TTATTCCACTGTAGATGTATACTGAGAGGATCAAAGGCCCTCTCAGAGTCACCCACTGAT
  GTTCCAAATCCTTGGTTAACAAGGTTAATTAAGAGAGAAGCACAATATTGCTGTAATATT
  ACAATTCCAGAAGCGTATCTTCTAGGGTCCTGTCTATTTAGTTAAAGAATAAAGCTCAGA
  CTCTTCGGGGATTCAGTACAACAAAGGTCCAGGAGCACTGCAGGCATCCTCCACATCATA
  ACAGCATTAATAGCAATTATTTCTAATTGGAGTGCATCTTGGCTGGACTGCGACAAAGGC
  CTGAAATTCAATTGTGGTTTTAAAATACCCATAAAATTGTCTAAACAAATTCAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138969 unedited
  GGTCATAATTGTATACCATCATATAGGCGGCCGCGTAATCCCGGGATCCGGCTTCTCCGC
  GGACAGCTAGGGAGAGTGTCCTGGGTGTCAGCCAGAACATGTCTTTCAACCTGCAATCAT
  CAAAGAAACTGTTCATTTTCTTAGGAAAATCACTGTTTAGTCTTCTGGAGGCTATGATTT
  TTGCCTTACTCCCAAAGCCACGGAAGAACGTTGCTGGTGAAATAGTCCTCATCACAGGTG
  CTGGAAGTGGACTCGGAAGGCTCTTAGCCTTGCAGTTTGCCCGGCTGGGATCTGTTCTTG
  TTCTCTGGGATATCAATAAGGAGGGGAATGAGGAAACATGTAAGATGGCTCGGGAAGCTG
  GAGCCACAAGAGTGCACGCCTATACCTGCGATTGCAGCCAAAAGGAAGGAGTGTATAGAG
  TAGCCGACCAGGTTAAAAAAGAAGTCGGCGATGTTTCCATCCTAATCAACAATGCCGGAA
  TCGTAACAGGCAAAAAGTTCCTTGACTGTCCAGATGAGCTTATGGAAAAGTCATTTGATG
  TGAATTTCAAAGCACATTTATGGACTTATAAAGCCTTTCTACCTGCTATGATTGCTAATG
  ACCATGGACATTTGGTTTGCATTTCAAGTTCAGCTGGATTAAGTGGAGTAAATGGGCTGG
  CAGATTACTGTGCAAGTAAATTTGCAGCCTTTGGGTTTGCTGAATCTGTATTTGTAGAAA
  CATTTGTCCAAAAACAAAAGGGGATCAAAACCACGATTGTGTGCCCCTTTTNTATAAAAA
  CTGGAATGTTTGAAGGTTGTACTACAGGCTGTCCTTCTCTGTTGCCAATTCTGGAACCAA
  ATATGCAGTTGAAAAATAGTAGAAGCTATTCTACAAGAAAAATGTACTTGTATATGCCAA
  AGTTGNTATACTTCATGATGTTTCTTAAAAGCTTT
  
• Restriction Sites: Please inquire
• ACCN: NM_138969
• ORF Size: 696 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_138969.1, NP_620419.1
• RefSeq Size: 2297
• RefSeq ORF: 696
• Locus ID: 195814
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. It encodes isoform 2, which is shorter than and has a distinct C-terminus compared to isoform 1.