RDHE2 (SDR16C5) (NM_138969) Human Untagged Clone

CAT#: SC317463

SDR16C5 (untagged)-Human short chain dehydrogenase/reductase family 16C, member 5 (SDR16C5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SDR16C5
• Synonyms: EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138969, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTTTCAACCTGCAATCATCAAAGAAACTGTTCATTTTCTTAGGAAAATCACTGTTTAGTCTTCTGG
  AGGCTATGATTTTTGCCTTACTCCCAAAGCCACGGAAGAACGTTGCTGGTGAAATAGTCCTCATCACAGG
  TGCTGGAAGTGGACTCGGAAGGCTCTTAGCCTTGCAGTTTGCCCGGCTGGGATCTGTTCTTGTTCTCTGG
  GATATCAATAAGGAGGGGAATGAGGAAACATGTAAGATGGCTCGGGAAGCTGGAGCCACAAGAGTGCACG
  CCTATACCTGCGATTGCAGCCAAAAGGAAGGAGTGTATAGAGTAGCCGACCAGGTTAAAAAAGAAGTCGG
  CGATGTTTCCATCCTAATCAACAATGCCGGAATCGTAACAGGCAAAAAGTTCCTTGACTGTCCAGATGAG
  CTTATGGAAAAGTCATTTGATGTGAATTTCAAAGCACATTTATGGACTTATAAAGCCTTTCTACCTGCTA
  TGATTGCTAATGACCATGGACATTTGGTTTGCATTTCAAGTTCAGCTGGATTAAGTGGAGTAAATGGGCT
  GGCAGATTACTGTGCAAGTAAATTTGCAGCCTTTGGGTTTGCTGAATCTGTATTTGTAGAAACATTTGTC
  CAAAAACAAAAGGGGATCAAAACCACGATTGTGTGCCCCTTTTTTATAAAAACTGGAATGTTTGAAGGTT
  GTACTACAGGCTGTCCTTCTCTGTTGCCAATTCTGGAACCAAAATATGCAGTTGAAAAAATAGTAGAAGC
  TATTCTACAAGAAAAAATGTACTTGTATATGCCAAAGTTGTTATACTTCATGATGTTTCTTAAAAGCTTT
  TTGCCCCTCAAGACAGGACTGCTTATAGCTGACTATTTGGGCATCCTTCATGCAATGGATGGCTTTGTTG
  ACCAAAAGAAGAAGCTCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_138969
• ORF Size: 930 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_138969.3, NP_620419.2
• RefSeq Size: 3535
• RefSeq ORF: 930
• Locus ID: 195814
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. It encodes isoform 2, which is shorter than and has a distinct C-terminus compared to isoform 1.