MNDA (NM_002432) Human Untagged Clone

CAT#: SC127417

MNDA (untagged)-Human myeloid cell nuclear differentiation antigen (MNDA)


  "NM_002432" in other vectors (7)

Reconstitution Protocol

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    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MNDA
Synonyms PYHIN3
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC127417 sequence for NM_002432 edited (data generated by NextGen Sequencing)
ATGGTGAATGAATACAAGAAAATTCTTTTGCTGAAAGGATTTGAGCTCATGGATGATTAT
CATTTTACATCAATTAAGTCCTTACTGGCCTATGATTTAGGACTAACTACAAAAATGCAA
GAGGAATACAACAGAATTAAGATTACAGATTTGATGGAAAAAAAGTTCCAAGGCGTTGCC
TGTCTAGACAAACTAATAGAACTTGCCAAAGATATGCCATCACTTAAAAACCTTGTTAAC
AATCTTCGAAAAGAGAAGTCAAAAGTTGCTAAGAAAATTAAAACACAAGAAAAAGCTCCA
GTGAAAAAAATAAACCAGGAAGAAGTGGGTCTTGCGGCACCTGCACCCACCGCAAGAAAC
AAACTGACATCGGAAGCAAGAGGGAGGATTCCTGTAGCTCAGAAAAGAAAAACTCCAAAC
AAAGAAAAGACTGAAGCCAAAAGGAATAAGGTGTCCCAAGAGCAGAGTAAGCCCCCAGGT
CCCTCAGGAGCCAGCACATCTGCAGCTGTGGATCATCCCCCACTACCCCAGACCTCATCA
TCAACTCCATCCAACACTTCGTTTACTCCGAATCAGGAAACCCAGGCCCAACGGCAGGTG
GATGCAAGAAGAAATGTTCCCCAAAACGACCCAGTGACAGTGGTGGTACTGAAAGCAACA
GCGCCATTTAAATACGAGTCCCCAGAAAATGGGAAAAGCACAATGTTTCATGCTACAGTG
GCCAGTAAGACTCAATATTTCCATGTGAAAGTCTTCGACATCAACTTGAAAGAGAAATTT
GTAAGGAAGAAGGTCATTACCATATCTGATTACTCTGAATGTAAAGGAGTAATGGAAATA
AAGGAAGCATCATCTGTGTCTGACTTTAATCAAAATTTTGAGGTCCCAAACAGAATTATC
GAAATAGCAAATAAAACTCCCAAGATCAGTCAACTTTACAAGCAAGCATCTGGAACAATG
GTGTATGGGTTGTTTATGTTACAAAAGAAAAGCGTACACAAGAAGAACACAATTTATGAA
ATACAGGATAATACAGGATCCATGGATGTAGTGGGGAGTGGAAAATGGCACAATATCAAG
TGTGAGAAAGGAGATAAACTTCGACTCTTCTGCCTTCAACTGAGAACAGTTGACCGCAAG
CTGAAACTGGTGTGTGGAAGTCACAGCTTCATCAAGGTCATCAAGGCCAAGAAAAACAAG
GAAGGACCAATGAATGTTAATTGA

Clone variation with respect to NM_002432.1
>OriGene 5' read for NM_002432 unedited
GGTTAGAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGATCAAGATT
GAGAGTGGCTCTAACAAGTGCCATTTTTCCTTGTTAGCTTTCATTTCTCAGCCCTTTACA
AGATTAAAATAGTCTGCAGTTTAATCTCTCCAAAGCTTTACGGACAGTGATTCTGTCCTA
AACAAGACAGTGACTCCAGGATTTCTGAAGACTATTGTGGAAGAAGCATCCATTAAGGCC
AAGCTATAACATCAGAAATGGTGAATGAATACAAGAAAATTCTTTTGCTGAAAGGATTTG
AGCTCATGGATGATTATCATTTTACATCAATTAAGTCCTTACTGGCCTATGATTTAGGAC
TAACTACAAAAATGCAAGAGGAATACAACAGAATTAAGATTACAGATTTGATGGAAAAAA
AGTTCCAAGGCGTTGCCTGTCTAGACAAACTAATAGAACTTGCCAAAGATATGCCATCAC
TTAAAAACCTTGTTAACAATCTTCGAAAAGAGAAGTCAAAAGTTGCTAAGAAAATTAAAA
CACAAGAAAAAGCTCCAGTGAAAAAAATAAACCAGGAAGAAGTGGGTCTTGCGGCACCTG
CACCCACCGCAAGAAACAAACTGACATCGGAAGCAAGAGGGAGGATTCCTGTAGCTCAGA
AAAGAAAAACTCCAAACANAGAANAGACTGAAGCCAAAAGGAATAAGGTGTCCCAAGAGC
AGAGTAAGCCCCCAGGTCCCTCAGGAGCCAGCACATCTGCAGCTGTGGATCATCCCCCAC
TACCCCAGACCTCATCATCAACTCCATCCCACACTTCGTTTACTCCGGTACACTCTTCCT
GGCCCTCTTCTCCATTTTTTTTTAACCCATCACAGTGCATTCCCCTGTTACTATNGGTAC
TCTCATGCATACCTCT
>OriGene 3' read for NM_002432 unedited
AAAGATATTTTATTTTTTGCCAGTGATGTCATAAAGCAAATGTAATATCTAAAAAAAAGG
AGAGTATAAGAAGAAATTTTATTCCAGAAAGCAAACTAATCTATAACTCAGTTATAAAAG
CTCTTAATATGCTAGAATATATCTACTGAAACATCATTTAAATGAATTACTGAAATTTAC
AAAATCACAGTTATTAACAACTTAATTGTTTTAAGCGGAAGTTGTTTGTTGCATTTCAGC
TTTCATATTTCAATTAACATTCATTGGTCCTTCCTTGTTTTTCTTGGCCTTGATGAACCT
TGATGAAGCTGTGACTTCCACACACCAGTTTCAGCTTGCGGTCAACTGTTCTCAGTTGAA
AGCAGAAGAAGTCGAAGTTTATCTCCTTTCTCACACTTGATATTGTGCCATTTTCCACTC
CCCACTACATCCATGGATCCTGTATTATCCTGTATTTCATAAATTGTGTTCTTCTTGTGT
ACGCTTTTCTTTTGTAACATAAACAACCCATACACCATTGTTCCAGATGCTTGCTTGTAA
AGTTGACTGATCTTGGGAGTTTTATTTGCTATTTCGATAATTCTGTTTGGGACCTCAAAA
TTTTGATTAAAGTCAGACACAGATGANTGCTTCCTTTATTTCCATTACTCCTTTACATTC
AGAGTAATCAGATATGGTAATGAACCTTCTTCCTTACAAATNTCTCTTTCAAGTTGATGT
CGAAAGACTNTCACATGGNAAATATTGAGTCTTACTGGGCCACTGTAGCATGATACATTN
NGTGCTNTTNCCATTTTCTGGGGGACTCGTATTAATTGGNNCGCTGNTGCTTTCAGGTAC
ACCACTGTCACTGGGGGTCGTTTAGGGGAACAATTTCTNCTGCATCCACNCTGCCGTTAG
CCNTGGAGTTNNCTGATTTCTGGGNTGGCGCAGAACATGAATATTAACTCTAAACTTTGA
GCANGAAGGNGGGCCCGGTGGGCTTCACCCTGTATTTCTACACTTTGGGAAGNCNAGGGG
GNTGGATACACAGGTCANAAAATACGAAACATCTCGCTAATAA
Restriction Sites ECoRI-NOT     
ACCN NM_002432
ORF Size 1224 bp
Insert Size 1800
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_002432.1, NP_002423.1
RefSeq Size 1670
RefSeq ORF 1224
Locus ID 4332
Domains PAAD_DAPIN, HIN
Protein Families Transcription Factors
Gene Summary The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]

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