MNDA (NM_002432) Human Untagged Clone

CAT#: SC323960

MNDA (untagged)-Human myeloid cell nuclear differentiation antigen (MNDA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MNDA
• Synonyms: PYHIN3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002432.1 CTACAATCAAGATTGAGAGTGGCTCTAACAAGTGCCATTTTTCCTTGTTAGCTTTCATTT
  CTCAGCCCTTTACAAGATTAAAATAGTCTGCAGTTTAATCTCTCCAAAGCTTTACGGACA
  GTGATTCTGTCCTAAACAAGACAGTGACTCCAGGATTTCTGAAGACTATTGTGGAAGAAG
  CATCCATTAAGGCCAAGCTATAACATCAGAAATGGTGAATGAATACAAGAAAATTCTTTT
  GCTGAAAGGATTTGAGCTCATGGATGATTATCATTTTACATCAATTAAGTCCTTACTGGC
  CTATGATTTAGGACTAACTACAAAAATGCAAGAGGAATACAACAGAATTAAGATTACAGA
  TTTGATGGAAAAAAAGTTCCAAGGCGTTGCCTGTCTAGACAAACTAATAGAACTTGCCAA
  AGATATGCCATCACTTAAAAACCTTGTTAACAATCTTCGAAAAGAGAAGTCAAAAGTTGC
  TAAGAAAATTAAAACACAAGAAAAAGCTCCAGTGAAAAAAATAAACCAGGAAGAAGTGGG
  TCTTGCGGCACCTGCACCCACCGCAAGAAACAAACTGACATCGGAAGCAAGAGGGAGGAT
  TCCTGTAGCTCAGAAAAGAAAAACTCCAAACAAAGAAAAGACTGAAGCCAAAAGGAATAA
  GGTGTCCCAAGAGCAGAGTAAGCCCCCAGGTCCCTCAGGAGCCAGCACATCTGCAGCTGT
  GGATCATCCCCCACTACCCCAGACCTCATCATCAACTCCATCCAACACTTCGTTTACTCC
  GAATCAGGAAACCCAGGCCCAACGGCAGGTGGATGCAAGAAGAAATGTTCCCCAAAACGA
  CCCAGTGACAGTGGTGGTACTGAAAGCAACAGCGCCATTTAAATACGAGTCCCCAGAAAA
  TGGGAAAAGCACAATGTTTCATGCTACAGTGGCCAGTAAGACTCAATATTTCCATGTGAA
  AGTCTTCGACATCAACTTGAAAGAGAAATTTGTAAGGAAGAAGGTCATTACCATATCTGA
  TTACTCTGAATGTAAAGGAGTAATGGAAATAAAGGAAGCATCATCTGTGTCTGACTTTAA
  TCAAAATTTTGAGGTCCCAAACAGAATTATCGAAATAGCAAATAAAACTCCCAAGATCAG
  TCAACTTTACAAGCAAGCATCTGGAACAATGGTGTATGGGTTGTTTATGTTACAAAAGAA
  AAGCGTACACAAGAAGAACACAATTTATGAAATACAGGATAATACAGGATCCATGGATGT
  AGTGGGGAGTGGAAAATGGCACAATATCAAGTGTGAGAAAGGAGATAAACTTCGACTCTT
  CTGCCTTCAACTGAGAACAGTTGACCGCAAGCTGAAACTGGTGTGTGGAAGTCACAGCTT
  CATCAAGGTCATCAAGGCCAAGAAAAACAAGGAAGGACCAATGAATGTTAATTGAAATAT
  GAAAGCTGAAATGCAACAAACAACTTCCGCTTAAAACAATTAAGTTGTTAATAACTGTGA
  TTTTGTAAATTTCAGTAATTCATTTAAATGATGTTTCAGTAGATATATTCTAGCATATTA
  AGAGCTTTTATAACTGAGTTATAGATTAGTTTGCTTTCTGGAATAAAATTTTCTTCTTAT
  ACTCTTCCTTTTTTTTAGATATTACATTTTGCTTTTATGACATTCACGAGGCAAAAAATA
  AAATATCTTTTTTTGAAGGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002432.1 unedited
  GACGCTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATCTACAATCAAGATTGAGAGTGGCTCTAACAAGTGCCATTTTTCCTTG
  TTAGCTTTCATTTCTCAGCCCTTTACAAGATTAAAATAGTCTGCAGTTTAATCTCTCCAA
  AGCTTTACGGACAGTGATTCTGTCCTAAACAAGACAGTGACTCCAGGATTTCTGAAGACT
  ATTGTGGAAGAAGCATCCATTAAGGCCAAGCTATAACATCAGAAATGGTGAATGAATACA
  AGAAAATTCTTTTGCTGAAAGGATTTGAGCTCATGGATGATTATCATTTTACATCAATTA
  AGTCCTTACTGGCCTATGATTTAGGACTAACTACAAAAATGCAAGAGGAATACAACAGAA
  TTAAGATTACAGATTTGATGGAAAAAAAGTTCCAAGGCGTTGCCTGTCTAGACAAACTAA
  TAGAACTTGCCAAAGATATGCCATCACTTAAAAACCTTGTTAACAATCTTCGAAAAGAGA
  AGTCAAAAGTTGCTAAGAAAATTAAAACACAAGAAAAAGCTCCAGTGAAAAAAATAAACC
  AGGAAGAAGTGGGTCTTGCGGCACCTGCACCCACCGCAAGAAACAAACTGACATCGGAAG
  CAAGAGGGAGGATTCCTGTAGCTCAGAAAAGAAAAACTCCAAACAAAGAAAAGACTGAAG
  CCAAAAGGAATAATGTGTCCCAAGAGCAGAGTAGCCCCCAGGTCCCTCAGGAGCCAGCAC
  ATCTGCAGCTGTGGATCATCCCCCACTACCCAGACTCATCATCAACTCATCAACACTCGT
  TTACTCGATCAGAAACCCAGGCCCACGCAGTGATGCAGAAGAATGTCCCAAACGACCATG
  ACAAGTGGTGGTACTGAAGCAACA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_002432
• ORF Size: 1224 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_002432.1, NP_002423.1
• RefSeq Size: 1670
• RefSeq ORF: 1224
• Locus ID: 4332
• Domains: PAAD_DAPIN, HIN
• Protein Families: Transcription Factors
• Gene Summary: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]