PNK (PNKP) (NM_007254) Human Untagged Clone

CAT#: SC128040

PNKP (untagged)-Human polynucleotide kinase 3'-phosphatase (PNKP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNKP
• Synonyms: AOA4; EIEE10; MCSZ; PNK
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128040 sequence for NM_007254 edited (data generated by NextGen Sequencing)
  ATGGGCGAGGTGGAGGCCCCGGGCCGCTTGTGGCTCGAGAGCCCCCCTGGGGGAGCGCCC
  CCCATCTTCCTGCCCTCGGACGGGCAAGCCCTGGTCCTGGGCAGGGGACCCCTGACCCAG
  GTTACGGACCGGAAGTGCTCCAGAACTCAAGTGGAGCTGGTCGCAGATCCTGAGACCCGG
  ACAGTGGCAGTGAAACAGCTGGGAGTTAACCCCTCAACTACCGGGACCCAGGAGTTGAAG
  CCGGGGTTGGAGGGCTCTCTGGGGGTGGGGGACACACTGTATTTGGTCAATGGCCTCCAC
  CCACTGACCCTGCGCTGGGAAGAGACCCGCACACCAGAATCCCAGCCAGATACTCCGCCT
  GGCACCCCTCTGGTGTCCCAAGATGAGAAGAGAGATGCTGAGCTGCCGAAGAAGCGTATG
  CGGAAGTCAAACCCCGGCTGGGAGAACTTGGAGAAGTTGCTAGTGTTCACCGCAGCTGGG
  GTGAAACCCCAGGGCAAGGTGGCTGGCTTTGATCTGGACGGGACGCTCATCACCACACGC
  TCTGGGAAGGTCTTTCCCACTGGCCCCAGTGACTGGAGGATCTTGTACCCAGAGATTCCC
  CGTAAGCTCCGAGAGCTGGAAGCCGAGGGCTACAAGCTGGTGATCTTCACCAACCAGATG
  AGCATCGGGCGCGGGAAGCTGCCAGCCGAGGAGTTCAAGGCCAAGGTGGAGGCTGTGGTG
  GAGAAGCTGGGGGTCCCCTTCCAGGTGCTGGTGGCCACGCACGCAGGCTTGTACCGGAAG
  CCGGTGACGGGCATGTGGGACCATCTGCAGGAGCAGGCCAACGACGGCACGCCCATATCC
  ATCGGGGACAGCATCTTTGTGGGAGACGCAGCCGGACGCCCGGCCAACTGGGCCCCGGGG
  CGGAAGAAGAAAGACTTCTCCTGCGCCGATCGCCTGTTTGCCCTCAACCTTGGCCTGCCC
  TTCGCCACGCCTGAGGAGTTCTTTCTCAAGTGGCCAGCAGCCGGCTTCGAGCTCCCAGCC
  TTTGATCCGAGGACTGTCTCCCGCTCAGGGCCTCTCTGCCTCCCCGAGTCCAGGGCCCTC
  CTGAGCGCCAGCCCGGAGGTGGTTGTCGCAGTGGGATTCCCTGGGGCCGGGAAGTCCACC
  TTTCTCAAGAAGCACCTCGTGTCGGCCGGATATGTCCACGTGAACAGGGACACGCTAGGC
  TCCTGGCAGCGCTGTGTGACCACGTGTGAGACAGCCCTGAAGCAAGGGAAACGGGTCGCC
  ATCGACAACACAAACCCAGACGCCGCGAGCCGCGCCAGGTACGTCCAGTGTGCCCGAGCC
  GCGGGCGTCCCCTGCCGCTGCTTCCTCTTCACCGCCACTCTGGAGCAGGCGCGCCACAAC
  AACCGGTTTCGAGAGATGACGGACTCCTCTCATATCCCCGTGTCAGACATGGTCATGTAT
  GGCTACAGGAAGCAGTTCGAGGCCCCAACGCTGGCTGAAGGCTTCTCTGCCATCCTGGAG
  ATCCCGTTCCGGCTATGGGTGGAGCCGAGGCTGGGGCGGCTGTACTGCCAGTTCTCCGAG
  GGCTGA
  
  Clone variation with respect to NM_007254.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007254 unedited
  ATTTTGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACCAGGGGGAGGGATGGA
  GCACGCGTCGTCGCCTGGGAAACGGGTCGACCCGCGGAAGGCGAGCGGGTGGGACTTCCG
  GAGCAGTTAATGGCCGGCACCCAGGATGGGCGAGGTGGAGGCCCCGGGCCGCTTGTGGCT
  CGAGAGCCCCCCTGGGGGAGCGCCCCCCATCTTCCTGCCCTCGGACGGGCAAGCCCTGGT
  CCTGGGCAGGGGACCCCTGACCCAGGTTACGGACCGGAAGTGCTCCAGAACTCAAGTGGA
  GCTGGTCGCAGATCCTGAGACCCGGACAGTGGCAGTGAAACAGCTGGGAGTTAACCCCTC
  AACTACCGGGACCCAGGAGTTGAAGCCGGGGTTGGAGGGCTCTCTGGGGGTGGGGGACAC
  ACTGTATTTGGTCAATGGCCTCCACCCACTGACCCTGCGCTGGGAAGAGACCCGCACACC
  AGAATCCCAGCCAGATACTCCGCCTGGCACCCCTCTGGTGTCCCAAGATGAGAAGAGAGA
  TGCTGAGCTGCCGAAGAAGCGTATGCGGAAGTCAAACCCCGGCTGGGAGAACTTGGAGAA
  GTTGCTAGTGTTCACCGCAGCTGGGGTGAAACCCNCAGGCAGGGTGGCTGGCTTTGATCT
  GGACGGGACGCTCATCACCACACGCTCTGGGAAGGTCTTTCCCACTGGCCCCAGTGACTG
  GAGGGATCTGTACCCAGAGATTCCCCCGTAGCTCCGAGAGCTGNAAGCCGAGGGCTACAA
  GCTGGTGATCTTNNCACACCAGATGAGCATCGGGCGCGGGAAGCTGCCCGCCCGAGAGTT
  CAAGGCCCAAGTGNNAGCTGTGGTTGAAAAACTGGGGGTTCCCTTTCAGGTGCTGTGGGC
  ACCCCACCAGGCTTGAACCGAAACCCGTAACCGCCATTGGGAACATTTTGAGAACAGGCC
  ACCACGGGCCCCCCATTCCTTCGGGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007254 unedited
  NAAGGCGTACTATGNACGCGGCCGCTATCTANGATCGGTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGGAAAAAAAGCGTTTATTGGGGAGGGGAG
  CTGGGCGGGGCTCACCCCTCGGAAAACTGGGAGTACAGCCGCCCCAGCCTGGGTTCCACC
  CATAGCCGGAACGGGATCTCCAGGATGGCAAAAAACCCTTCACCCAGCGTTGGGGCCTCA
  AACTGTTTCCTGGAGCCATACATGACCATGTTTGACACGGGGATATGAAAGGAGTCCGTC
  ATCTTTCAAAACCGGTTGTTGGGGCCCCCCTGCTCCAAAGGGGCGGGGAAAAGGAAACAG
  CGGCAGGGGACCCCCGGGGCTCGGGCACACTGGACGTACCTGGCGCGGTTCGGGGCGTTT
  GGGTTTGGGTTGTCAATGGCAACCCGTTTCCCTTGCTTAAGGGCTGTCTCACACGTGGTC
  ACACAGGGCTGCCAGGAGCCTAACGGGTCCCTGTTCACGTGGACATATCCGGCCGACACG
  AGGGGCTTCTTGAGAAAGGGGGACTTCCCGGCCCCAGGGAATCCCACTGGGACAACCACC
  TCCGGGCTGGCGCTCAGGAGGGCCCTGGACTCGGGGAGGCATAAAGGCCCTGAGCGGGAA
  ACAGCCCTCGGATCAAAGGCTGGGAGCTCGAACCCGGCTGCTGGCCACTTGAAAAAGTAC
  TCCTCNAGCGTGGGCAAAGGGGAGGCCAAGGTTGAGGGCAAAAAGGGCGATCGGCGGCAG
  GAAAAATCTTTCTTCTTTCCGCCCCGGGCCCCAATTGGCCCGGCGTCCCGGTTGGGGTTT
  CCAAAAAAAAAGCTGTCCCCCATGGGATATGGGGCG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_007254
• ORF Size: 1566 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007254.2, NP_009185.2
• RefSeq Size: 1745
• RefSeq ORF: 1566
• Locus ID: 11284
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. [provided by RefSeq, Sep 2010]