PNK (PNKP) (NM_007254) Human Untagged Clone

CAT#: SC323976

PNKP (untagged)-Human polynucleotide kinase 3'-phosphatase (PNKP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNKP
• Synonyms: AOA4; EIEE10; MCSZ; PNK
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007254.2 GGAACCGACCGCCGCCGGCCGGGTTGCAGGCGGGGCACCTCGGGCAGGACCTCCCTGGTC
  GGAAGTGGCCGTGAGCCCAAGCCGCGGTCCCGGGCCGGCACCCAGGATGGGCGAGGTGGA
  GGCCCCGGGCCGCTTGTGGCTCGAGAGCCCCCCTGGGGGAGCGCCCCCCATCTTCCTGCC
  CTCGGACGGGCAAGCCCTGGTCCTGGGCAGGGGACCCCTGACCCAGGTTACGGACCGGAA
  GTGCTCCAGAACTCAAGTGGAGCTGGTCGCAGATCCTGAGACCCGGACAGTGGCAGTGAA
  ACAGCTGGGAGTTAACCCCTCAACTACCGGGACCCAGGAGTTGAAGCCGGGGTTGGAGGG
  CTCTCTGGGGGTGGGGGACACACTGTATTTGGTCAATGGCCTCCACCCACTGACCCTGCG
  CTGGGAAGAGACCCGCACACCAGAATCCCAGCCAGATACTCCGCCTGGCACCCCTCTGGT
  GTCCCAAGATGAGAAGAGAGATGCTGAGCTGCCGAAGAAGCGTATGCGGAAGTCAAACCC
  CGGCTGGGAGAACTTGGAGAAGTTGCTAGTGTTCACCGCAGCTGGGGTGAAACCCCAGGG
  CAAGGTGGCTGGCTTTGATCTGGACGGGACGCTCATCACCACACGCTCTGGGAAGGTCTT
  TCCCACTGGCCCCAGTGACTGGAGGATCTTGTACCCAGAGATTCCCCGTAAGCTCCGAGA
  GCTGGAAGCCGAGGGCTACAAGCTGGTGATCTTCACCAACCAGATGAGCATCGGGCGCGG
  GAAGCTGCCAGCCGAGGAGTTCAAGGCCAAGGTGGAGGCTGTGGTGGAGAAGCTGGGGGT
  CCCCTTCCAGGTGCTGGTGGCCACGCACGCAGGCTTGTACCGGAAGCCGGTGACGGGCAT
  GTGGGACCATCTGCAGGAGCAGGCCAACGACGGCACGCCCATATCCATCGGGGACAGCAT
  CTTTGTGGGAGACGCAGCCGGACGCCCGGCCAACTGGGCCCCGGGGCGGAAGAAGAAAGA
  CTTCTCCTGCGCCGATCGCCTGTTTGCCCTCAACCTTGGCCTGCCCTTCGCCACGCCTGA
  GGAGTTCTTTCTCAAGTGGCCAGCAGCCGGCTTCGAGCTCCCAGCCTTTGATCCGAGGAC
  TGTCTCCCGCTCAGGGCCTCTCTGCCTCCCCGAGTCCAGGGCCCTCCTGAGCGCCAGCCC
  GGAGGTGGTTGTCGCAGTGGGATTCCCTGGGGCCGGGAAGTCCACCTTTCTCAAGAAGCA
  CCTCGTGTCGGCCGGATATGTCCACGTGAACAGGGACACGCTAGGCTCCTGGCAGCGCTG
  TGTGACCACGTGTGAGACAGCCCTGAAGCAAGGGAAACGGGTCGCCATCGACAACACAAA
  CCCAGACGCCGCGAGCCGCGCCAGGTACGTCCAGTGTGCCCGAGCCGCGGGCGTCCCCTG
  CCGCTGCTTCCTCTTCACCGCCACTCTGGAGCAGGCGCGCCACAACAACCGGTTTCGAGA
  GATGACGGACTCCTCTCATATCCCCGTGTCAGACATGGTCATGTATGGCTACAGGAAGCA
  GTTCGAGGCCCCAACGCTGGCTGAAGGCTTCTCTGCCATCCTGGAGATCCCGTTCCGGCT
  ATGGGTGGAGCCGAGGCTGGGGCGGCTGTACTGCCAGTTCTCCGAGGGCTGAGCCCCGCC
  CAGCTCCCCTCCACAATAAACGCTGTTTCTCCTTGAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007254.2 unedited
  GGCCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATGGAACCGACCGCCGCCGGCCGGGTTGCAGGCGGGGCACCTCGGGCAG
  GACCTCCCTGGTCGGAAGTGGCCGTGAGCCCAAGCCGCGGTCCCGGGCCGGCACCCAGGA
  TGGGCGAGGTGGAGGCCCCGGGCCGCTTGTGGCTCGAGAGCCCCCCTGGGGGAGCGCCCC
  CCATCTTCCTGCCCTCGGACGGGCAAGCCCTGGTCCTGGGCAGGGGACCCCTGACCCAGG
  TTACGGACCGGAAGTGCTCCAGAACTCAAGTGGAGCTGGTCGCAGATCCTGAGACCCGGA
  CAGTGGCAGTGAAACAGCTGGGAGTTAACCCCTCAACTACCGGGACCCAGGAGTTGAAGC
  CGGGGTTGGAGGGCTCTCTGGGGGTGGGGGACACACTGTATTTGGTCAATGGCCTCCACC
  CACTGACCCTGCGCTGGGAAGAGACCCGCACACCAGAATCCCAGCCAGATACTCCGCCTG
  GCACCCCTCTGGTGTCCCAAGATGAGAAGAGAGATGCTGAGCTGCCGAAGAAGCGTATGC
  GGAAGTCAAACCCCGGCTGGGAGAACTTGGAGAAGTTGCTAGTGTTCACCGCAGCTGGGG
  GTGAAACCCCAGGGCAAGGTGGCTGGCTTTGATCTGGACGGGACGCTCATCACCCACACG
  CTCTGGGAAGGTCTTTCCACTGGCCCCAGTGACTGGAGGATCTTGTACCCAGAGATTCCC
  GTAAGCTCCGAGAGCTGCAGCCCGAGGGCTACCAGCTTGTTGATCTTCACTCACCAGATT
  GACCATCTGGCGCCGGAAGCCTGCCAGCCCGAGAGTTCACAGGCCAGGTTGCAGGCCTGT
  GGTCGAGAAGACCTGATGGTCCCATCCAGTGCCGCTGTCAACCACAGCAGCTTTGTCACG
  AACTCCGTGCACTGTAATGTGGTAACATCTGCCTGACATCATCGCA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_007254
• ORF Size: 1566 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007254.2, NP_009185.2
• RefSeq Size: 1745
• RefSeq ORF: 1566
• Locus ID: 11284
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. [provided by RefSeq, Sep 2010]