MTUS1 (NM_001001925) Human Untagged Clone

CAT#: SC300344

MTUS1 (untagged)-Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTUS1
• Synonyms: ATBP; ATIP; ATIP3; ICIS; MP44; MTSG1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001001925, the custom clone sequence may differ by one or more nucleotides
  ATGACTGATGATAATTCAGATGATAAAATAGAAGATGAATTGCAAACCTTCTTTACCAGT
  GATAAAGATGGAAATACACATGCATACAACCCGAAATCACCACCTACACAAAACTCTTCA
  GCCAGCAGTGTGAACTGGAATTCTGCCAACCCAGATGACATGGTGGTTGATTATGAAACT
  GACCCTGCTGTAGTTACTGGTGAAAATATTTCTTTAAGCCTTCAGGGTGTTGAAGTATTT
  GGTCATGAAAAGTCTTCTAGTGATTTCATTAGTAAGCAGGTGTTAGATATGCATAAAGAT
  TCTATTTGTCAGTGTCCTGCACTTGTAGGTACTGAGAAGCCCAAATATCTGCAACACAGT
  TGTCATTCCCTAGAAGCAGTTGAGGGCCAGAGTGTTGAGCCATCTTTGCCTTTTGTGTGG
  AAGCCTAATGACAATTTGAACTGTGCAGGCTACTGTGATGCCTTGGAGCTAAACCAAACA
  TTTGACATGACAGTGGATAAAGTTAACTGCACCTTTATATCACATCATGCCATCGGAAAG
  AGTCAGTCCTTCCATACTGCTGGAAGCCTGCCACCAACTGGTAGGAGAAGTGGAAGTACA
  TCTTCTTTATCCTATTCCACTTGGACATCTTCCCATTCTGATAAGACGCATGCAAGAGAA
  ACTACTTATGATAGAGAAAGCTTTGAAAACCCTCAAGTCACACCATCAGAAGCCCAAGAC
  ATGACTTACACAGCATTTTCTGATGTGGTGATGCAAAGTGAGGTTTTTGTTTCAGATATT
  GGAAATCAGTGTGCATGTTCTTCAGGAAAGGTCACCAGTGAGTACACAGATGGATCACAA
  CAAAGACTAGTTGGAGAAAAGGAGACACAAGCACTAACACCAGTTTCTGATGGCATGGAA
  GTCCCCAATGATTCTGCATTACAAGAGTTCTTTTGTTTATCCCATGATGAATCCAATAGC
  GAACCACATTCACAGAGCTCATACAGGCACAAGGAAATGGGCCAAAATCTGAGAGAGACA
  GTGTCCTATTGTCTTATTGATGATGAATGCCCTTTAATGGTGCCAGCTTTTGATAAGAGC
  GAAGCTCAAGTGCTGAACCCAGAGCATAAAGTCACTGAGACTGAAGACACACAAATGGTC
  TCCAAAGGAAAGGATTTGGGAACCCAAAATCATACCTCAGAATTGATTCTAAGTAGCCCG
  CCAGGACAAAAGGTGGGCTCGTCATTTGGACTGACTTGGGATGCAAATGATATGGTCATT
  AGCACAGACAAAACGATGTGCATGTCAACACCAGTCCTAGAACCCACAAAAGTAACCTTT
  TCTGTTTCACCGATTGAAGCGACGGAGAAATGTAAGAAAGTGGAGAAGGGTAATCGAGGG
  CTTAAAAACATACCAGACTCGAAGGAGGCACCTGTGAACCTGTGTAAACCCAGTTTAGGA
  AAATCAACAATCAAAACGAATACCCCAATAGGCTGCAAAGTTAGAAAAACTGAAATTATA
  AGTTACCCAAGACCAAACTTCAAGAATGTCAAAGCAAAAGTTATGTCTAGAGCAGTGTTG
  CAGCCCAAAGATGCTGCTTTATCAAAGGTCACGCCCAGACCTCAGCAGACCAGTGCCTCA
  TCACCCTCATCAGTGAATTCAAGACAACAAACAGTCTTGAGCAGAACACCGAGATCTGAC
  TTGAATGCAGACAAAAAAGCAGAAATTCTAATTAACAAGACACATAAGCAGCAGTTTAAT
  AAACTCATTACTAGCCAGGCTGTGCATGTTACAACTCATTCTAAAAATGCTTCACACAGG
  GTTCCAAGAACAACATCTGCCGTGAAATCGAATCAGGAAGATGTTGACAAAGCCAGTTCT
  TCTAACTCAGCATGCGAGACCGGGTCCGTTTCTGCGTTGTTTCAGAAGATCAAAGGCATA
  CTCCCTGTTAAAATGGAAAGTGCAGAATGTTTGGAAATGACCTATGTTCCCAACATTGAT
  AGGATTAGCCCTGAAAAGAAGGGTGAAAAAGAAAATGGGACATCTATGGAAAAACAAGAG
  CTGAAACAAGAGATTATGAATGAGACTTTTGAATATGGTTCTCTGTTTTTGGGCTCTGCT
  TCAAAAACAACGACCACCTCAGGTAGGAATATATCCAAGCCTGACTCCTGCGGTTTGAGG
  CAAATAGCTGCTCCAAAAGCCAAAGTGGGGCCCCCTGTTTCCTGTTTGAGGCGGAACAGT
  GACAATAGAAATCCCAGTGCTGATCGAGCCGTATCTCCTCAGAGGATCAGGCGTGTGTCC
  AGTTCTGCTGGTAATGCCGCTGTCATCAAATATGAGGAGAAACCTCCAAAACCAGCATTT
  CAGAATGGTTCCTCAGGATCCTTTTATTTGAAGCCTTTGGTATCCAGGGCTCATGTTCAC
  TTGATGAAAACTCCTCCAAAAGGTCCTTCGAGAAAAAATTTATTTACAGCTCTTAATGCA
  GTTGAAAAGAGCAGGCAAAAGAATCCTCGAAGCTTATGTATCCAGCCACAGACAGCTCCC
  GATGCGCTGCCCCCTGAGAAAACACTTGAATTGACGCAATATAAAACAAAATGTGAAAAC
  CAAAGTGGATTTATCCTGCAGCTCAAGCAGCTTCTTGCCTGTGGTAATACCAAGTTTGAG
  GCATTGACAGTTGTGATTCAGCACCTGCTGTCTGAGCGGGAGGAAGCACTGAAACAACAC
  AAAACCCTATCTCAAGAACTTGTTAACCTCCGGGGAGAGCTAGTCACTGCTTCAACCACC
  TGTGAGAAATTAGAAAAAGCCAGGAATGAGTTACAAACAGTGTATGAAGCATTCGTCCAG
  CAGCACCAGGCTGAAAAAACAGAACGAGAGAATCGGCTTAAAGAGTTTTACACCAGGGAG
  TATGAAAAGCTTCGGGACACTTACATTGAAGAAGCAGAGAAGTACAAAATGCAATTGCAA
  GAGCAGTTTGACAACTTAAATGCTGCGCATGAAACCTCTAAGTTGGAAATTGAAGCTAGC
  CACTCAGAGAAACTTGAATTGCTAAAGAAGGCCTATGAAGCCTCCCTTTCAGAAATTAAG
  AAAGGCCATGAAATAGAAAAGAAATCGCTTGAAGATTTACTTTCTGAGAAGCAGGAATCG
  CTAGAGAAGCAAATCAATGATCTGAAGAGTGAAAATGATGCTTTAAATGAAAAATTGAAA
  TCAGAAGAACAAAAAAGAAGAGCAAGAGAAAAAGCAAATTTGAAAAATCCTCAGATCATG
  TATCTAGAACAGGAGTTAGAAAGCCTGAAAGCTGTGTTAGAGATCAAGAATGAGAAACTG
  CATCAACAGGACATCAAGTTAATGAAAATGGAGAAACTGGTGGACAACAACACAGCATTG
  GTTGACAAATTGAAGCGTTTCCAGCAGGAGAATGAAGAATTGAAAGCTCGGATGGACAAG
  CACATGGCAATCTCAAGGCAGCTTTCCACGGAGCAGGCTGTTCTGCAAGAGTCGCTGGAG
  AAGGAGTCGAAAGTCAACAAGCGACTCTCTATGGAAAACGAGGAGCTTCTGTGGAAACTG
  CACAATGGGGACCTGTGTAGCCCCAAGAGATCCCCCACATCCTCCGCCATCCCTTTGCAG
  TCACCAAGGAATTCGGGCTCCTTCCCTAGCCCCAGCATTTCACCCAGATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001001925
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001001925.1, NP_001001925.1
• RefSeq Size: 6229 bp
• RefSeq ORF: 3651 bp
• Locus ID: 57509
• Cytogenetics: 8p22
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. It encodes isoform 2 which lacks an internal segment, compared to isoform 1.