MTUS1 (NM_001001931) Human Untagged Clone

CAT#: SC300349

MTUS1 (untagged)-Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTUS1
• Synonyms: ATBP; ATIP; ATIP3; ICIS; MP44; MTSG1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001001931, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACTGTACCAGGAGGATTTCGCAGTTGTACAGAAACTGATATTTCTTCAAAAATCTTTATCAATTCTA
  CACTCACCCCACCGGCTGGTTCAGAGAGGCACTATGATGCTACCTTATTGACACTGCTGGTCGTGGGATC
  GTACAGCCTTTGTATAATTCCTTTGTTAGCCACGTTTACTGGGAAAAAAACTGGTAATGCCGCTGTCATC
  AAATATGAGGAGAAACCTCCAAAACCAGCATTTCAGAATGGTTCCTCAGGATCCTTTTATTTGAAGCCTT
  TGGTATCCAGGGCTCATGTTCACTTGATGAAAACTCCTCCAAAAGGTCCTTCGAGAAAAAATTTATTTAC
  AGCTCTTAATGCAGTTGAAAAGAGCAGGCAAAAGAATCCTCGAAGCTTATGTATCCAGCCACAGACAGCT
  CCCGATGCGCTGCCCCCTGAGAAAACACTTGAATTGACGCAATATAAAACAAAATGTGAAAACCAAAGTG
  GATTTATCCTGCAGCTCAAGCAGCTTCTTGCCTGTGGTAATACCAAGTTTGAGGCATTGACAGTTGTGAT
  TCAGCACCTGCTGTCTGAGCGGGAGGAAGCACTGAAACAACACAAAACCCTATCTCAAGAACTTGTTAAC
  CTCCGGGGAGAGCTAGTCACTGCTTCAACCACCTGTGAGAAATTAGAAAAAGCCAGGAATGAGTTACAAA
  CAGTGTATGAAGCATTCGTCCAGCAGCACCAGGCTGAAAAAACAGAACGAGAGAATCGGCTTAAAGAGTT
  TTACACCAGGGAGTATGAAAAGCTTCGGGACACTTACATTGAAGAAGCAGAGAAGTACAAAATGCAATTG
  CAAGAGCAGTTTGACAACTTAAATGCTGCGCATGAAACCTCTAAGTTGGAAATTGAAGCTAGCCACTCAG
  AGAAACTTGAATTGCTAAAGAAGGCCTATGAAGCCTCCCTTTCAGAAATTAAGAAAGGCCATGAAATAGA
  AAAGAAATCGCTTGAAGATTTACTTTCTGAGAAGCAGGAATCGCTAGAGAAGCAAATCAATGATCTGAAG
  AGTGAAAATGATGCTTTAAATGAAAAATTGAAATCAGAAGAACAAAAAAGAAGAGCAAGAGAAAAAGCAA
  ATTTGAAAAATCCTCAGATCATGTATCTAGAACAGGAGTTAGAAAGCCTGAAAGCTGTGTTAGAGATCAA
  GAATGAGAAACTGCATCAACAGGACATCAAGTTAATGAAAATGGAGAAACTGGTGGACAACAACACAGCA
  TTGGTTGACAAATTGAAGCGTTTCCAGCAGGAGAATGAAGAATTGAAAGCTCGGATGGACAAGCACATGG
  CAATCTCAAGGCAGCTTTCCACGGAGCAGGCTGTTCTGCAAGAGTCGCTGGAGAAGGAGTCGAAAGTCAA
  CAAGCGACTCTCTATGGAAAACGAGGAGCTTCTGTGGAAACTGCACAATGGGGACCTGTGTAGCCCCAAG
  AGATCCCCCACATCCTCCGCCATCCCTTTGCAGTCACCAAGGAATTCGGGCTCCTTCCCTAGCCCCAGCA
  TTTCACCCAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001001931
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001001931.2, NP_001001931.1
• RefSeq Size: 4022 bp
• RefSeq ORF: 1554 bp
• Locus ID: 57509
• Cytogenetics: 8p22
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4), also known as ATIP4, lacks several 5' exons but has an alternate 5' exon, compared to variant 1. It encodes isoform 4 which has a much shorter and distinct N-terminus, compared to isoform 1.