TLR6 (NM_006068) Human Untagged Clone

CAT#: SC303729

TLR6 (untagged)-Human toll-like receptor 6 (TLR6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TLR6
• Synonyms: CD286
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006068 edited
  ATGACCAAAGACAAAGAACCTATTGTTAAAAGCTTCCATTTTGTTTGCCTTATGATCATA
  ATAGTTGGAACCAGAATCCAGTTCTCCGACGGAAATGAATTTGCAGTAGACAAGTCAAAA
  AGAGGTCTTATTCATGTTCCAAAAGACCTACCGCTGAAAACCAAAGTCTTAGATATGTCT
  CAGAACTACATCGCTGAGCTTCAGGTCTCTGACATGAGCTTTCTATCAGAGTTGACAGTT
  TTGAGACTTTCCCATAACAGAATCCAGCTACTTGATTTAAGTGTTTTCAAGTTCAACCAG
  GATTTAGAATATTTGGATTTATCTCATAATCAGTTGCAAAAGATATCCTGCCATCCTATT
  GTGAGTTTCAGGCATTTAGATCTCTCATTCAATGATTTCAAGGCCCTGCCCATCTGTAAG
  GAATTTGGCAACTTATCACAACTGAATTTCTTGGGATTGAGTGCTATGAAGCTGCAAAAA
  TTAGATTTGCTGCCAATTGCTCACTTGCATCTAAGTTATATCCTTCTGGATTTAAGAAAT
  TATTATATAAAAGAAAATGAGACAGAAAGTCTACAAATTCTGAATGCAAAAACCCTTCAC
  CTTGTTTTTCACCCAACTAGTTTATTCGCTATCCAAGTGAACATATCAGTTAATACTTTA
  GGGTGCTTACAACTGACTAATATTAAATTGAATGATGACAACTGTCAAGTTTTCATTAAA
  TTTTTATCAGAACTCACCAGAGGTTCAACCTTACTGAATTTTACCCTCAACCACATAGAA
  ACGACTTGGAAATGCCTGGTCAGAGTCTTTCAATTTCTTTGGCCCAAACCTGTGGAATAT
  CTCAATATTTACAATTTAACAATAATTGAAAGCATTCGTGAAGAAGATTTTACTTATTCT
  AAAACGACATTGAAAGCATTGACAATAGAACATATCACGAACCAAGTTTTTCTGTTTTCA
  CAGACAGCTTTGTACACCGTGTTTTCTGAGATGAACATTATGATGTTAACCATTTCAGAT
  ACACCTTTTATACACATGCTGTGTCCTCATGCACCAAGCACATTCAAGTTTTTGAACTTT
  ACCCAGAACGTTTTCACAGATAGTATTTTTGAAAAATGTTCCACGTTAGTTAAATTGGAG
  ACACTTATCTTACAAAAAAATGGATTAAAAGACCTTTTCAAAGTAGGTCTCATGACGAAG
  GATATGCCTTCTTTGGAAATACTGGATGTTAGCTGGAACTCTTTGGAATCTGGTAGACAT
  AAAGAAAACTGCACTTGGGTTGAGAGTATAGTGGTGTTAAATTTGTCTTCAAATATGCTT
  ACTGACTCTGTTTTCAGATGTTTACCTCCCAGGATCAAGGTACTTGATCTTCACAGCAAT
  AAAATAAAGAGCGTTCCTAAACAAGTCGTAAAACTGGAAGCTTTGCAAGAACTCAATGTT
  GCTTTCAATTCTTTAACTGACCTTCCTGGATGTGGCAGCTTTAGCAGCCTTTCTGTATTG
  ATCATTGATCACAATTCAGTTTCCCACCCATCGGCTGATTTCTTCCAGAGCTGCCAGAAG
  ATGAGGTCAATAAAAGCAGGGGACAATCCATTCCAATGTACCTGTGAGCTAAGAGAATTT
  GTCAAAAATATAGACCAAGTATCAAGTGAAGTGTTAGAGGGCTGGCCTGATTCTTATAAG
  TGTGACTACCCAGAAAGTTATAGAGGAAGCCCACTAAAGGACTTTCACATGTCTGAATTA
  TCCTGCAACATAACTCTGCTGATCGTCACCATCGGTGCCACCATGCTGGTGTTGGCTGTG
  ACTGTGACCTCCCTCTGCATCTACTTGGATCTGCCCTGGTATCTCAGGATGGTGTGCCAG
  TGGACCCAGACTCGGCGCAGGGCCAGGAACATACCCTTAGAAGAACTCCAAAGAAACCTC
  CAGTTTCATGCTTTTATTTCATATAGTGAACATGATTCTGCCTGGGTGAAAAGTGAATTG
  GTACCTTACCTAGAAAAAGAAGATATACAGATTTGTCTTCATGAGAGGAACTTTGTCCCT
  GGCAAGAGCATTGTGGAAAATATCATCAACTGCATTGAGAAGAGTTACAAGTCCATCTTT
  GTTTTGTCTCCCAACTTTGTCCAGAGTGAGTGGTGCCATTACGAACTCTATTTTGCCCAT
  CACAATCTCTTTCATGAAGGATCTAATAACTTAATCCTCATCTTACTGGAACCCATTCCA
  CAGAACAGCATTCCCAACAAGTACCACAAGCTGAAGGCTCTCATGACGCAGCGGACTTAT
  TTGCAGTGGCCCAAGGAGAAAAGCAAACGTGGGCTCTTTTGGGCTAACATTAGAGCCGCT
  TTTAATATGAAATTAACACTAGTCACTGAAAACAATGATGTGAAATCTTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_006068
• ORF Size: 2391 bp
• Insert Size: 2400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_006068.2, NP_006059.2
• RefSeq Size: 2753
• RefSeq ORF: 2391
• Locus ID: 10333
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Toll-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations. [provided by RefSeq, Jan 2011]