ALDH1A2 (NM_003888) Human Untagged Clone

CAT#: SC309760

ALDH1A2 (untagged)-Human aldehyde dehydrogenase 1 family, member A2 (ALDH1A2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH1A2
• Synonyms: RALDH(II); RALDH2; RALDH2-T
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109995 sequence for NM_170697 edited (data generated by NextGen Sequencing)
  ATGGATGCTTCAGAAAGGGGACGTCTGTTGGATAAGCTTGCAGACTTGGTGGAACGGGAC
  AGGGCAGTTCTTGCAACCATGGAATCCCTAAATGGTGGCAAACCATTCCTGCAAGCTTTT
  TATGTGGATTTGCAGGGCGTCATCAAAACCTTTCGATATTACGCAGGCTGGGCTGATAAA
  ATTCATGGGATGACCATTCCTGTAGATGGAGACTATTTTACCTTTACAAGACATGAACCC
  ATTGGAGTGTGTGGACAGATCATCCCATGGAACTTCCCCCTGCTGATGTTTGCCTGGAAA
  ATAGCTCCAGCTTTGTGCTGTGGCAATACAGTAGTTATTAAGCCAGCAGAGCAAACACCA
  CTCAGTGCACTCTACATGGGAGCCCTCATCAAGGAGGCTGGCTTTCCTCCCGGGGTCATC
  AATATTTTGCCAGGATATGGGCCAACGGCTGGGGCAGCAATAGCTTCTCACATTGGCATA
  GACAAGATTGCATTCACAGGGTCTACTGAGGTTGGAAAGCTTATCCAAGAAGCAGCTGGA
  AGAAGTAATTTGAAGAGAGTAACTCTGGAACTTGGAGGCAAAAGTCCTAATATTATTTTT
  GCTGATGCTGACTTGGACTATGCTGTGGAGCAGGCCCACCAGGGTGTGTTCTTCAATCAA
  GGTCAGTGCTGCACTGCAGGCTCTCGCATCTTCGTGGAGGAGTCCATCTATGAGGAGTTT
  GTGAGAAGAAGCGTGGAGCGGGCCAAGAGGCGCGTAGTGGGGAGTCCCTTTGACCCCACC
  ACTGAGCAGGGTCCCCAGATTGATAAGAAACAGTACAACAAGATCTTGGAACTCATCCAG
  AGTGGTGTGGCTGAGGGCGCCAAGCTGGAATGTGGAGGCAAAGGACTGGGCCGAAAGGGG
  TTTTTCATTGAGCCCACAGTGTTTTCCAACGTCACTGATGATATGCGGATTGCCAAGGAG
  GAGATCTTTGGCCCTGTTCAGGAAATTTTGAGATTTAAGACGATGGATGAAGTTATCGAA
  AGAGCCAATAACTCAGACTTTGGACTCGTAGCAGCTGTCTTTACTAATGACATCAACAAG
  GCCCTCACAGTGTCTTCTGCAATGCAAGCTGGGACTGTTTGGATCAATTGTTACAATGCC
  TTAAATGCCCAGAGCCCCTTTGGGGGATTCAAGATGTCTGGAAATGGGAGAGAAATGGGA
  GAATTTGGCTTGCGGGAGTACTCAGAAGTTAAGACGGTGACAGTAAAGATCCCCCAGAAG
  AACTCCTAA
  
  Clone variation with respect to NM_170697.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_170697 unedited
  GTTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCCGCCACCAT
  GACTTCCAGCAAGATAGAGATGCCCGGCGAGGTGAAGGCCGACCCCGCCGCCCTCATGGC
  GTCGCTGCACCTCCTGCCGTCGCCCACGCCCAATCTCGAAATTAAGTACACCAAGATCTT
  TATAAACAACGAGTGGCAGAACTCAGAGAGTGGGAGAGTGTTCCCTGTCTATAATCCAGC
  CACAGGAGAACAGGTGTGTGAAGTTCAAGAAGCAGACAAGGCAGATATAGACAAAGCAGT
  GCAGGCAGCCCGCCTGGCTTTCTCTCTTGGTTCAGTGTGGAGAAGGATGGATGCTTCAGA
  AAGGGGACGTCTGTTGGATAAGCTTGCAGACTTGGTGGAACGGGACAGGGCAGTTCTTGC
  AACCATGGAATCCCTAAATGGTGGCAAACCATTCCTGCAAGCTTTTTATGTGGATTTGCA
  GGGCGTCATCAAAACCTTTCGATATTACGCAGGCTGGGCTGATAAAATTCATGGGATGAC
  CATTCCTGTAGATGGAGACTATTTTACCTTTACAAGACATGAACCCATTGGAGTGTGTGG
  ACAGATCATCCCATGGAACTTCCCCCTGCTGATGTTTGCCTGGAAAATAGCTCCAGCTTT
  GTGCTGTGGCAATACAGTAGTTATTAAGCCAGCAGAGCAAACACCACTCAGTGCACTCTA
  CATGGGAGCCCTCATCAAGGAGGCTGGCTTTCCTCCCGGGGTCATCAATATTTTGCCAGG
  ATATGGGCCAACGGCTGGGGCAGNCATAGCTTCTCACATTGGCATAGACAAGATGCATTC
  ACAGGGTCTACNTGGGNTNGGNAAAGCTATNCNAGAAGCAGCTGGAAGAAGTATTTGAAA
  GAGAGTACTCTGGAACTTGNAGGCAAAGTNCTAAATATATTNTTGCTGATGCTGACTTGG
  ACTATGCTGGGGAGCAGGCCACCAAGGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_170697 unedited
  ATTTAGCTNTGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTACAC
  AATATAAATGCTTTATTGCTAGCACAGAGGTTTCTTTTTAAGTAAATTAAAAGAAATAAA
  TCTTCATTTTCACATTTTTTGTTGCAGTCCAAAGGTAACTAGTTGGTTAGTGGCTATGTC
  CACTTGGACACATGCTACAGGAGGGCAGCATTCACATGGAAGCACTCAGAAATACGGCAT
  CTGTCAGGGCTCACGGCACTGGGCTGCTGAATGCACTGTCGTTTGTAAATAACAGCAAGT
  GGAGACTTTAAAACATCATGGATAGATAAGAGTTATAAATAGAAAACTGGTACGGTTAAG
  AAGCAGAAGATCGTTAAATACAGAAGGCTATATATATGTTGCCCATATTCCACATACTCT
  GGGTTATGTTTGGTACTTTTAAATAAATGATCTGCATTTAGGTTAGAGACTGGATTGGAT
  TTGACAGCTGGAAAGATGGAAGAAGGGATGGAAGAAGGAAAGGAAGCTAACACTTCCCAC
  ATCAAACTGGTGGAGTCACTGGAAAGCAGAAGAGGAGTATGTGGATGGGAAGAAAGGGAG
  GCGGGCCTGCTTTACTCCCTGCAAGCTGTAGGCCATGGCCTGCCCAGTGAGGGGCAAGAA
  TGGGGTGTGACAGAGGAGCTCAGTGGAGCACGGCAGTCCTGGCACAATGGAACTTGGCAA
  ATGGAAAAGGAAACCCCTAGGCTTGGCCAGATTTTCCAAGGTCACTGCCAATAGATACAG
  GGCACATTATGATAGATGTACAGTGTGACAGACCAAAATCACACCTGCAGCAGTTATTGG
  TGGTAGAGGTTCAGAAGGTACAGATTCCCACTACAGAAATATTCATTTAATATAATTGTT
  GCCCATATTAGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_003888
• ORF Size: 1557 bp
• Insert Size: 3400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003888.2, NP_003879.2
• RefSeq Size: 3398
• RefSeq ORF: 1557
• Locus ID: 8854
• Domains: aldedh
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Retinol metabolism
• Gene Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).