Proprotein convertase PC4 (PCSK4) (NM_017573) Human Untagged Clone

CAT#: SC311408

PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCSK4
• Synonyms: PC4; SPC5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017573 edited
  ATGCGGCCCGCCCCGATTGCGCTGTGGCTGCGCCTGGTCTTGGCCCTGGCCCTTGTCCGC
  CCCCGGGCTGTGGGGTGGGCCCCGGTCCGAGCCCCCATCTATGTCAGCAGCTGGGCCGTC
  CAGGTGTCCCAGGGTAACCGGGAGGTCGAGCGCCTGGCACGCAAATTCGGCTTCGTCAAC
  CTGGGGCCGATCTTCCCTGACGGGCAGTACTTTCACCTGCGGCACCGGGGCGTGGTCCAG
  CAGTCCCTGACCCCGCACTGGGGCCACCGCCTGCACCTGAAGAAAAACCCCAAGGTGCAG
  TGGTTCCAGCAGCAGACGCTGCAGCGGCGGGTGAAACGCTCTGTCGTGGTGCCCACGGAC
  CCCTGGTTCTCCAAGCAGTGGTACATGAACAGCGAGGCCCAACCAGACCTGAGCATCCTG
  CAGGCCTGGAGTCAGGGGCTGTCAGGCCAGGGCATCGTGGTCTCTGTGCTGGACGATGGC
  ATCGAGAAGGACCACCCGGACCTCTGGGCCAACTACGACCCCCTGGCCAGCTATGACTTC
  AATGACTACGACCCGGACCCCCAGCCCCGCTACACCCCCAGCAAAGAGAACCGGCACGGG
  ACCCGCTGTGCTGGGGAGGTGGCCGCGATGGCCAACAATGGCTTCTGTGGTGTGGGGGTC
  GCTTTCAACGCCCGAATCGGAGGCGTACGGATGCTGGACGGTACCATCACCGATGTCATC
  GAGGCCCAGTCGCTGAGCCTGCAGCCGCAGCACATCCACATTTACAGCGCCAGCTGGGGT
  CCCGAGGACGACGGCCGCACGGTGGACGGCCCCGGCATCCTCACCCGCGAGGCCTTCCGG
  CGTGGTGTGACCAAGGGCCGCGGCGGGCTGGGCACGCTCTTCATCTGGGCCTCGGGCAAC
  GGCGGCCTGCACTACGACAACTGCAACTGCGACGGCTACACCAACAGCATCCACACGCTT
  TCCGTGGGCAGCACCACCCAGCAGGGCCGCGTGCCCTGGTACAGCGAAGCCTGCGCCTCC
  ACCCTCACCACCACCTACAGCAGCGGCGTGGCCACCGACCCCCAGATCGTCACCACGGAC
  CTGCATCACGGGTGCACAGACCAGCACACGGGCACCTCGGCCTCAGCCCCACTGGCGGCC
  GGCATGATCGCCCTAGCGCTGGAGGCCAACCCGTTCCTGACGTGGAGAGACATGCAGCAC
  CTGGTGGTCCGCGCGTCCAAGCCGGCGCACCTGCAGGCCGAGGACTGGAGGACCAACGGC
  GTGGGGCGCCAAGTGAGCCATCACTACGGATACGGGCTGCTGGACGCCGGGCTGCTGGTG
  GACACCGCCCGCACCTGGCTGCCCACCCAGCCGCAGAGGAAGTGCGCCGTCCGGGTCCAG
  AGCCGCCCCACCCCCATCCTGCCGCTGATCTACATCAGGGAAAACGTATCGGCCTGCGCC
  GGCCTCCACAACTCCATCCGCTCGCTGGAGCACGTGCAGGCGCAGCTGACGCTGTCCTAC
  AGCCGGCGCGGAGACCTGGAGATCTCGCTCACCAGCCCCATGGGCACGCGCTCCACACTC
  GTGGCCATACGACCCTTGGACGTCAGCACTGAAGGCTACAACAACTGGGTCTTCATGTCC
  ACCCACTTCTGGGATGAGAACCCACAGGGCGTGTGGACCCTGGGCCTAGAGAACAAGGGC
  TACTATTTCAACACGGGGACGTTGTACCGCTACACGCTGCTGCTCTATGGGACGGCCGAG
  GACATGACAGCGCGGCCTACAGGCCCCCAGGTGACCAGCAGCGCGTGTGTGCAGCGGGAC
  ACAGAGGGGCTGTGCCAGGCGTGTGACGGCCCCGCCTACATCCTGGGACAGCTCTGCCTG
  GCCTACTGCCCCCCGCGGTTCTTCAACCACACAAGGCTGGTGACCGCTGGGCCTGGGCAC
  ACGGCGGCGCCCGCGCTGAGGGTCTGCTCCAGCTGCCATGCCTCCTGCTACACCTGCCGC
  GGCGGCTCCCCGAGGGACTGCACCTCCTGTCCCCCATCCTCCACGCTGGACCAGCAGCAG
  GGCTCCTGCATGGGACCCACCACCCCCGACAGCCGCCCCCGGCTTAGAGCTGCCGCCTGT
  CCCCACCACCGCTGCCCAGCCTCGGCCATGGTGCTGAGCCTCCTGGCCGTGACCCTCGGA
  GGCCCCGTCCTCTGCGGCATGTCCATGGACCTCCCACTATACGCCTGGCTCTCCCGTGCC
  AGGGCCACCCCCACCAAACCCCAGGTCTGGCTGCCAGCTGGAACCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_017573
• ORF Size: 2268 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017573.3, NP_060043.2
• RefSeq Size: 2674
• RefSeq ORF: 2268
• Locus ID: 54760
• Protein Families: Druggable Genome, Protease
• Gene Summary: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. [provided by RefSeq, Jan 2014]