Proprotein convertase PC4 (PCSK4) (NM_017573) Human Untagged Clone

CAT#: SC318233

PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCSK4
• Synonyms: PC4; SPC5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017573, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGGCCCGCCCCGATTGCGCTGTGGCTGCGCCTGGTCTTGGCCCTGGCCCTTGTCCGCCCCCGGGCTG
  TGGGGTGGGCCCCGGTCCGAGCCCCCATCTATGTCAGCAGCTGGGCCGTCCAGGTGTCCCAGGGTAACCG
  GGAGGTCGAGCGCCTGGCACGCAAATTCGGCTTCGTCAACCTGGGGCCGATCTTCCCTGACGGGCAGTAC
  TTTCACCTGCGGCACCGGGGCGTGGTCCAGCAGTCCCTGACCCCGCACTGGGGCCACCGCCTGCACCTGA
  AGAAAAACCCCAAGGTGCAGTGGTTCCAGCAGCAGACGCTGCAGCGGCGGGTGAAACGCTCTGTCGTGGT
  GCCCACGGACCCCTGGTTCTCCAAGCAGTGGTACATGAACAGCGAGGCCCAACCAGACCTGAGCATCCTG
  CAGGCCTGGAGTCAGGGGCTGTCAGGCCAGGGCATCGTGGTCTCTGTGCTGGACGATGGCATCGAGAAGG
  ACCACCCGGACCTCTGGGCCAACTACGACCCCCTGGCCAGCTATGACTTCAATGACTACGACCCGGACCC
  CCAGCCCCGCTACACCCCCAGCAAAGAGAACCGGCACGGGACCCGCTGTGCTGGGGAGGTGGCCGCGATG
  GCCAACAATGGCTTCTGTGGTGTGGGGGTCGCTTTCAACGCCCGAATCGGAGGCGTACGGATGCTGGACG
  GTACCATCACCGATGTCATCGAGGCCCAGTCGCTGAGCCTGCAGCCGCAGCACATCCACATTTACAGCGC
  CAGCTGGGGTCCCGAGGACGACGGCCGCACGGTGGACGGCCCCGGCATCCTCACCCGCGAGGCCTTCCGG
  CGTGGTGTGACCAAGGGCCGCGGCGGGCTGGGCACGCTCTTCATCTGGGCCTCGGGCAACGGCGGCCTGC
  ACTACGACAACTGCAACTGCGACGGCTACACCAACAGCATCCACACGCTTTCCGTGGGCAGCACCACCCA
  GCAGGGCCGCGTGCCCTGGTACAGCGAAGCCTGCGCCTCCACCCTCACCACCACCTACAGCAGCGGCGTG
  GCCACCGACCCCCAGATCGTCACCACGGACCTGCATCACGGGTGCACAGACCAGCACACGGGCACCTCGG
  CCTCAGCCCCACTGGCGGCCGGCATGATCGCCCTAGCGCTGGAGGCCAACCCGTTCCTGACGTGGAGAGA
  CATGCAGCACCTGGTGGTCCGCGCGTCCAAGCCGGCGCACCTGCAGGCCGAGGACTGGAGGACCAACGGC
  GTGGGGCGCCAAGTGAGCCATCACTACGGATACGGGCTGCTGGACGCCGGGCTGCTGGTGGACACCGCCC
  GCACCTGGCTGCCCACCCAGCCGCAGAGGAAGTGCGCCGTCCGGGTCCAGAGCCGCCCCACCCCCATCCT
  GCCGCTGATCTACATCAGGGAAAACGTATCGGCCTGCGCCGGCCTCCACAACTCCATCCGCTCGCTGGAG
  CACGTGCAGGCGCAGCTGACGCTGTCCTACAGCCGGCGCGGAGACCTGGAGATCTCGCTCACCAGCCCCA
  TGGGCACGCGCTCCACACTCGTGGCCATACGACCCTTGGACGTCAGCACTGAAGGCTACAACAACTGGGT
  CTTCATGTCCACCCACTTCTGGGATGAGAACCCACAGGGCGTGTGGACCCTGGGCCTAGAGAACAAGGGC
  TACTATTTCAACACGGGGACGTTGTACCGCTACACGCTGCTGCTCTATGGGACGGCCGAGGACATGACAG
  CGCGGCCTACAGGCCCCCAGGTGACCAGCAGCGCGTGTGTGCAGCGGGACACAGAGGGGCTGTGCCAGGC
  GTGTGACGGCCCCGCCTACATCCTGGGACAGCTCTGCCTGGCCTACTGCCCCCCGCGGTTCTTCAACCAC
  ACAAGGCTGGTGACCGCTGGGCCTGGGCACACGGCGGCGCCCGCGCTGAGGGTCTGCTCCAGCTGCCATG
  CCTCCTGCTACACCTGCCGCGGCGGCTCCCCGAGGGACTGCACCTCCTGTCCCCCATCCTCCACGCTGGA
  CCAGCAGCAGGGCTCCTGCATGGGACCCACCACCCCCGACAGCCGCCCCCGGCTTAGAGCTGCCGCCTGT
  CCCCACCACCGCTGCCCAGCCTCGGCCATGGTGCTGAGCCTCCTGGCCGTGACCCTCGGAGGCCCCGTCC
  TCTGCGGCATGTCCATGGACCTCCCACTATACGCCTGGCTCTCCCGTGCCAGGGCCACCCCCACCAAACC
  CCAGGTCTGGCTGCCAGCTGGAACCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_017573
• ORF Size: 2268 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017573.4, NP_060043.2
• RefSeq Size: 2716
• RefSeq ORF: 2268
• Locus ID: 54760
• Protein Families: Druggable Genome, Protease
• Gene Summary: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. [provided by RefSeq, Jan 2014]