CTIP1 (BCL11A) (NM_138559) Human Untagged Clone

CAT#: SC312609

BCL11A (untagged)-Human B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCL11A
• Synonyms: BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; CTIP1; DILOS; EVI9; HBFQTL5; ZNF856
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138559 edited
  CTCGAGCTTTTTTTTTTTTTTTTTTTTTTTGCTTAAAAAAAAGCCATGACGGCTCTCCCA
  CAATTCATCTTCCCTGCGCCATCTTTGTATTATTTCTAATTTATTTTGGATGTCAAAAGG
  CACTGATGAAGATATTTTCTCTGGAGTCTCCTTCTTTCTAACCCGGCTCTCCCGATGTGA
  ACCGAGCCGTCGTCCGCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCGCCCCGCAGCCCA
  CCATGTCTCGCCGCAAGCAAGGCAAACCCCAGCACTTAAGCAAACGGGAATTCTCGCCCG
  AGCCTCTTGAAGCCATTCTTACAGATGATGAACCAGACCACGGCCCGTTGGGAGCTCCAG
  AAGGGGATCATGACCTCCTCACCTGTGGGCAGTGCCAGATGAACTTCCCATTGGGGGACA
  TTCTTATTTTTATCGAGCACAAACGGAAACAATGCAATGGCAGCCTCTGCTTAGAAAAAG
  CTGTGGATAAGCCACCTTCCCCTTCACCAATCGAGATGAAAAAAGCATCCAATCCCGTGG
  AGGTTGGCATCCAGGTCACGCCAGAGGATGACGATTGTTTATCAACGTCATCTAGAGGAA
  TTTGCCCCAAACAGGAACACATAGCAGATAAACTTCTGCACTGGAGGGGCCTCTCCTCCC
  CTCGTTCTGCACATGGAGCTCTAATCCCCACGCCTGGGATGAGTGCAGAATATGCCCCGC
  AGGGTATTTGTAAAGATGAGCCCAGCAGCTACACATGTACAACTTGCAAACAGCCATTCA
  CCAGTGCATGGTTTCTCTTGCAACACGCACAGAACACTCATGGATTAAGAATCTACTTAG
  AAAGCGAACACGGAAGTCCCCTGACCCCGCGGGTTCTTCACACACCCCCATTCGGCGTAG
  TACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTT
  CTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGCGTGCCGCCCAGTCGACGTCAGC
  GTGGTCTGTCATCCTGCTAGTTTGTGATGTTTTCTGACAGTAGCCTCCAAGAAGCCGTTG
  TGCGAAGACAGAGTCCTGCAGAGTCCTTCCAGCCTAGGCCTGCAGCGCCATTTTATTTAT
  ATTTTTTAATAAAAAGTAAAAACAAAAAAACAGACCCACATTGGAACAGTGAATCAGTCC
  CATAGAGAGGGCCCGTGGACCATCGCTGTCATGAGTGATGCCCTGGCCCTTCTGAAACCA
  GCCAACCTAATTACCTGTATTGTGGAAATGCGCATGAGTCCCCAACCCCTTGTTTCTATA
  CATTCTATGTTGTCTTTTAAAAAGTGTGCTTAACATTGACACAATAAATGTTGGAGCTTT
  AGGTGGT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138553 unedited
  ACAATTCATCTTCCCTGCGCCATCTTTGTATTATTTCTAATTTATTTTGGATGTCAAAAG
  GCACTGATGAAGATATTTTCTCTGGAGTCTCCTTCTTTCTAACCCGGCTCTCCCGATGTG
  AACCGAGCCGTCGTCCGCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCGCCCCGCAGCCC
  ACCATGTCTCGCCGCAAGCAAGGCAAACCCCAGCACTTAAGCAAACGGGAATTCTCGCCC
  GAGCCTCTTGAAGCCATTCTTACAGATGATGAACCAGACCACGGCCCGTTGGGAGCTCCA
  GAAGGGGATCATGACCTCCTCACCTGTGGGCAGTGCCAGATGAACTTCCCATTGGGGGAC
  ATTCTTATTTTTATCGAGCACAAACGGAAACAATGCAATGGCAGCCTCTGCTTAGAAAAA
  GCTGTGGATAAGCCACCTTCCCCTTCACCAATCGAGATGAAAAAAGCATCCAATCCCGTG
  GAGGTTGGCATCCAGGTCACGCCAGAGGATGACGATTGTTTATCAACGTCATCTAGAGGA
  ATTTGCCCCAAACAGGAACACATAGCAGATAAACTTCTGCACTGGAGGGGCCTCTNCTCC
  CCTCGTTCTGCACATGGAGCTCCTATCCCCACGCCTGGGATGAGTGCAGAATATGCCCCG
  CAGGGTATTTTGTAAGATGAGCCCAGCAGTTCACATGTACCACTTGCAACAGCCATTACC
  AGTGCATGGTTTCTCTTGCACACGCACANAACTCATGATTANAAATCTCTAAAAGCACCC
  GNAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_138553 unedited
  AAGCTAACACTTNNATGAGCTCATGTTAAGCACACTTTTTAAAGCCAACATAGGAAGTAT
  AGAAACAAGGGGTTGGGGACTCATGCGCATTTCCACAATACAGGTAATTAGGTTGGCTGG
  GGGGCAGAAGGGCCAGGGCATCACTCATGACAGCGATGGTCCACGGGCCCTCTCTATGGG
  ACTGATTCACTGTTCCAATGTGGGTCTGTTCTTTTGTTTTTACTTTTTATTAAAAAATAT
  AAATAAGGGGGCGCTGCACGCCTAGGCTGGAAGGACTCTGCAGGACTCTGTCTTCGCACA
  ACGGCTTCTTGGAGGCTACTGTCAGAAAACATCACAAACTAGCAGGATGACAGACCACGC
  TGACGTCGACTGGGCGGCACGCGTGCACCCCACCCCTGGGGGCTTCAAATTTTCTCAGAA
  CTTAAGGGCTCTCGAGCTTCCATCCGAAAACCTCGCCCACATCTTGAGCTCTCTGGGTAC
  TACGTCGAATGGGGGTGTGTGAACAACCCGCGGGGTCAAGGGACTTTCGTGTTCGCTTTC
  TAAGTACACCCTTAACTCCATGACTGATTTGTGCGTGCTGTAAGAGAATCCATGCACCGC
  CGAACGCCCTGCTCGCAAGGTGAACACCCCCACCCTGTGCGCTAATCTTCTCCCACCCCC
  CCGCCGTGTTTATCCTGCACTCATTCCACGCTTCGCCATCTCACTCCCATGTCCCTAACC
  GGCGGCTGATAGGCCCCTTAACACAGACACCTTACTGGCATGAGTACCCGCGTGCGGCCA
  TCCCCCCAGGCGACCGAGTCAACCATCCGCCCCCCTCCGGCCCGGATCTGTCTGCCTACT
  CCTCCCGTTCTGCCGCGCCCCTCCTCTCCNCTTCGCAGACGGCAATGTCGCCTCTCCCCC
  ACTCTTCTCTCTACGCGCCTGCACTCCTCTTCCCTACTGTTGCTCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_138559
• ORF Size: 732 bp
• Insert Size: 1400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_138559.1.

Reference Data

• RefSeq: NM_138559.1, NP_612569.1
• RefSeq Size: 2358
• RefSeq ORF: 732
• Locus ID: 53335
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) is also known as B-cell lymphoma/leukaemia 11A short form (BCL11A-S). It lacks a large portion of the 3' coding region which introduces a frameshift, and it contains a different 3' UTR region when compared to variant 1. The encoded isoform (3) has a truncated and distinct C-terminus, as compared to isoform 1.