RNF14 (NM_004290) Human Untagged Clone

CAT#: SC313633

RNF14 (untagged)-Human ring finger protein 14 (RNF14), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF14
• Synonyms: ARA54; HFB30; HRIHFB2038; TRIAD2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004290, the custom clone sequence may differ by one or more nucleotides
  ATGTCGTCAGAAGATCGAGAAGCTCAGGAGGATGAATTGCTGGCCCTGGCAAGTATTTAC
  GATGGAGATGAATTTAGAAAAGCAGAGTCTGTCCAAGGTGGAGAAACCAGGATCTATTTG
  GATTTGCCACAGAATTTCAAGATATTTGTGAGCGGCAATTCAAATGAGTGTCTCCAGAAT
  AGTGGCTTTGAATACACCATTTGCTTTCTGCCTCCACTTGTGCTGAACTTTGAACTGCCA
  CCAGATTATCCATCCTCTTCCCCACCTTCATTCACACTTAGTGGCAAATGGCTGTCACCA
  ACTCAGCTATCTGCTCTATGCAAGCACTTAGACAACCTATGGGAAGAACACCGTGGCAGC
  GTGGTCCTGTTTGCCTGGATGCAATTTCTTAAGGAAGAGACCCTAGCATACTTGAATATT
  GTCTCTCCTTTTGAGCTCAAGATTGGTTCTCAGAAAAAAGTGCAGAGAAGGACAGCTCAA
  GCTTCTCCCAACACAGAGCTAGATTTTGGAGGAGCTGCTGGATCTGATGTAGACCAAGAG
  GAAATTGTGGATGAGAGAGCAGTGCAGGATGTGGAATCACTGTCAAATCTGATCCAGGAA
  ATCTTGGACTTTGATCAAGCTCAGCAGATAAAATGCTTTAATAGTAAATTGTTCCTGTGC
  AGTATCTGTTTCTGTGAGAAGCTGGGTAGTGAATGCATGTACTTCTTGGAGTGCAGGCAT
  GTGTACTGCAAAGCCTGTCTGAAGGACTACTTTGAAATCCAGATCAGAGATGGCCAGGTT
  CAATGCCTCAACTGCCCAGAACCAAAGTGCCCTTCGGTGGCCACTCCTGGTCAGGTCAAA
  GAGTTAGTGGAAGCAGAGTTATTTGCCCGTTATGACCGCCTTCTCCTCCAGTCCTCCTTG
  GACCTGATGGCAGATGTGGTGTACTGCCCCCGGCCGTGCTGCCAGCTGCCTGTGATGCAG
  GAACCTGGCTGCACCATGGGTATCTGCTCCAGCTGCAATTTTGCCTTCTGTACTTTGTGC
  AGGTTGACCTACCATGGGGTCTCCCCATGTAAGGTGACTGCAGAGAAATTAATGGACTTA
  CGAAATGAATACCTGCAAGCGGATGAGGCTAATAAAAGACTTTTGGATCAAAGGTATGGT
  AAGAGAGTGATTCAGAAGGCACTGGAAGAGATGGAAAGTAAGGAGTGGCTAGAGAAGAAC
  TCAAAGAGCTGCCCATGTTGTGGAACTCCCATAGAGAAATTAGACGGATGTAACAAGATG
  ACATGTACTGGCTGTATGCAATATTTCTGTTGGATTTGCATGGGTTCTCTCTCTAGAGCA
  AACCCTTACAAACATTTCAATGACCCTGGTTCACCATGTTTTAACCGGCTGTTTTATGCT
  GTGGATGTTGACGACGATATTTGGGAAGATGAGGTAGAAGAC
  
• Restriction Sites: Please inquire
• ACCN: NM_004290
• ORF Size: 1425 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004290.3, NP_004281.1
• RefSeq Size: 3144
• RefSeq ORF: 1425
• Locus ID: 9604
• Domains: RING, IBR, RWD
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.