TMEM16A (ANO1) (NM_018043) Human Untagged Clone

CAT#: SC316851

ANO1 (untagged)-Human anoctamin 1, calcium activated chloride channel (ANO1), transcript variant 1


  "NM_018043" in other vectors (11)

Reconstitution Protocol

SC316851 is the updated version of SC314998.

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ANO1
Synonyms DOG1; ORAOV2; TAOS2; TMEM16A
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_018043 edited
ATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTG
GAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTG
AAAATCCATGCCCCCTGGAACGTGCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATG
CCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCT
GTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACC
ATGAAGAGACTCTCCTATCCCTTCTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGAT
AAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTTGAAGAGA
ACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTG
TACGCGGCTGCATACCCACTGCACGATGGAGACTACAACGGTGAAAACGTCGAGTTCAAC
GACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTACCAGCCC
ATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGC
GTGTACACCCAGATGCTCATCCCTGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGA
TGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACACAATATC
ACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCC
ACGGCCCGCGCCAGCCACCTCTTCGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATG
GCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACTCAACTAC
CGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGAGGCTGTCAAGGATCATCCTAGAGCT
GAATACGAAGCCAGAGTCTTGGAGAAGTCTCTGAAGAAAGAGTCCAGAAACAAAGAGACT
GACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCC
ATCATCTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGGATC
TCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCCCTCCGTGCGGTCCAACATCCGGGTC
ACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTG
TATGGCTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTT
GAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAAGTTTGTGAATTCCTACACCCCCATC
TTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATT
TTCCGTTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATC
CAGCTCAGCATCATCATGCTGGGGAAACAGCTGATCCAGAACAACCTGTTCGAGATCGGC
ATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGAC
CACGAGGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTC
GCGGGCCTCACCCCAGAGTACATGGAAATGATCATCCAGTTTGGCTTCGTCACCCTGTTT
GTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGC
CTGGACGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGAC
ATCGGAATCTGGTACAATATCCTCAGAGGCATTGGGAAGCTTGCTGTCATCATCAATGCC
TTCGTGATCTCCTTCACGTCTGACTTCATCCCGCGCCTGGTGTACCTCTACATGTACAGT
AAGAACGGGACCATGCACGGCTTCGTCAACCACACCCTCTCCTCCTTCAACGTCAGTGAC
TTCCAGAACGGCACGGCCCCCAATGACCCCCTGGACCTGGGCTACGAGGTGCAGATCTGC
AGGTATAAAGACTACCGAGAGCCGCCGTGGTCGGAAAACAAGTACGACATCTCCAAGGAC
TTCTGGGCCGTCCTGGCAGCCCGGCTGGCGTTTGTCATCGTCTTCCAGAACCTGGTCATG
TTCATGAGCGACTTTGTGGACTGGGTCATCCCGGACATCCCCAAGGACATCAGCCAGCAG
ATCCACAAGGAGAAGGTGCTCATGGTGGAGCTGTTCATGCGGGAGGAGCAAGACAAGCAG
CAGCTGCTGGAAACCTGGATGGAGAAGGAGCGGCAGAAGGACGAGCCGCCGTGCAACCAC
CACAACACCAAAGCCTGCCCAGACAGCCTCGGCAGCCCAGCCCCCAGCCATGCCTACCAC
GGGGGCGTCCTGTAG
Restriction Sites Please inquire     
ACCN NM_018043
ORF Size 2883 bp
Insert Size 5200
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation It is not a varient.
Reference Data
RefSeq NM_018043.4, NP_060513.4
RefSeq Size 4811
RefSeq ORF 2883
Locus ID 55107
Domains DUF590
Protein Families Transmembrane
Gene Summary Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. [UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.

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