Karyopherin beta 3 (IPO5) (NM_002271) Human Untagged Clone

CAT#: SC318500

IPO5 (untagged)-Human importin 5 (IPO5)


  "NM_002271" in other vectors (7)

Reconstitution Protocol

USD 1,100.00

5 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IPO5
Synonyms IMB3; imp5; KPNB3; Pse1; RANBP5
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_002271, the custom clone sequence may differ by one or more nucleotides
ATGCCTGAGGATCAAGTTGGAAAACTAGAAGCAACAGAAAACACAATAAGCGCAATGGCG
GCGGCCGCGGCGGAGCAGCAACAGTTCTACCTGCTCCTGGGAAACCTGCTCAGCCCCGAC
AATGTGGTCCGGAAACAGGCAGAGGAAACCTATGAGAATATCCCAGGCCAGTCAAAGATC
ACATTCCTCTTACAAGCCATCAGAAATACAACAGCTGCTGAAGAGGCTAGACAAATGGCC
GCCGTTCTCCTAAGACGTCTCTTGTCCTCTGCATTTGATGAAGTCTATCCAGCACTTCCC
TCTGATGTTCAGACTGCCATCAAGAGTGAGCTACTCATGATTATTCAGATGGAAACACAA
TCTAGCATGAGGAAAAAAGTTTGTGATATTGCGGCAGAACTGGCCAGGAATTTAATAGAT
GAGGATGGCAATAACCAGTGGCCCGAAGGTTTGAAGTTCCTTTTTGATTCAGTCAGCTCT
CAAAATGTGGGACTGCGGGAAGCTGCCCTTCACATTTTCTGGAACTTTCCTGGAATTTTT
GGGAACCAGCAACAACACTATTTAGATGTCATCAAACGAATGTTAGTTCAGTGTATGCAA
GATCAGGAACACCCGTCGATCAGGACGTTATCTGCTAGAGCTACAGCTGCATTTATACTT
GCAAATGAGCATAATGTTGCTCTGTTCAAACATTTTGCAGACTTGCTACCGGGATTCCTA
CAGGCGGTAAATGACTCGTGCTACCAGAATGATGATTCTGTCCTAAAATCCCTCGTTGAG
ATTGCAGATACTGTTCCAAAGTATTTGCGTCCTCACTTGGAAGCAACTCTACAGCTAAGT
CTAAAGTTGTGTGGAGACACTAGCCTCAACAATATGCAACGCCAGCTTGCCCTTGAAGTG
ATCGTCACCCTCTCTGAGACTGCAGCTGCTATGTTAAGAAAACATACCAATATTGTTGCA
CAGACTATTCCTCAGATGTTAGCAATGATGGTTGATTTGGAAGAAGATGAGGACTGGGCA
AATGCAGATGAACTAGAAGATGATGATTTTGACAGCAATGCAGTTGCAGGCGAGAGTGCT
CTAGATCGAATGGCTTGCGGACTTGGTGGAAAGCTCGTTCTGCCGATGATCAAGGAACAC
ATTATGCAAATGCTTCAAAATCCTGACTGGAAATACCGGCATGCAGGATTGATGGCCTTA
TCTGCCATTGGTGAAGGGTGCCACCAGCAAATGGAAGGAATTCTAAATGAGATCGTAAAT
TTTGTTTTACTTTTTCTCCAGGATCCTCATCCAAGAGTAAGGTATGCAGCCTGTAATGCC
GTGGGACAGATGGCTACAGATTTTGCACCTGGTTTCCAAAAGAAATTTCATGAGAAGGTG
ATTGCAGCTCTGCTGCAGACCATGGAAGACCAAGGCAATCAACGTGTGCAGGCCCATGCA
GCTGCTGCCCTCATTAACTTTACTGAAGACTGTCCCAAGTCACTACTTATTCCATACTTG
GATAATTTGGTGAAACATCTGCATTCCATTATGGTACTGAAGCTTCAAGAGCTGATTCAG
AAAGGCACCAAGTTAGTTTTGGAACAAGTTGTGACATCCATTGCATCAGTTGCCGATACT
GCAGAAGAAAAATTTGTCCCCTACTATGATTTATTTATGCCATCACTGAAGCACATCGTT
GAGAATGCGGTTCAAAAAGAACTGAGACTTCTGAGAGGAAAAACTATTGAATGCATTAGC
CTCATTGGTCTGGCTGTTGGGAAGGAAAAATTCATGCAGGATGCATCAGATGTGATGCAG
CTTTTGTTAAAGACCCAGACAGACTTCAATGATATGGAAGATGATGATCCTCAGATCTCT
TACATGATCTCAGCATGGGCCAGAATGTGCAAAATCCTTGGAAAAGAATTTCAGCAATAC
CTTCCAGTGGTTATGGGGCCTTTAATGAAGACGGCTTCAATTAAGCCCGAAGTAGCCCTT
TTAGATACCCAAGACATGGAGAATATGAGTGATGATGATGGTTGGGAATTTGTGAACCTT
GGAGATCAGCAAAGCTTTGGTATTAAAACTGCAGGACTAGAAGAAAAATCAACTGCTTGC
CAGATGTTGGTTTGCTATGCTAAGGAGTTAAAGGAAGGCTTTGTGGAGTACACCGAACAG
GTTGTCAAACTGATGGTCCCTTTACTGAAATTTTATTTCCACGATGGTGTTCGAGTGGCA
GCAGCGGAATCCATGCCTCTTCTCCTGGAGTGTGCAAGAGTCCGTGGTCCTGAGTATCTC
ACACAGATGTGGCATTTTATGTGTGATGCTCTAATTAAGGCCATTGGTACAGAACCAGAT
TCAGACGTCCTCTCAGAAATAATGCATTCTTTTGCAAAGTGCATTGAAGTAATGGGAGAT
GGATGCCTTAATAATGAACACTTTGAAGAACTGGGAGGTATATTGAAAGCAAAGCTTGAA
GAACATTTTAAAAATCAAGAATTACGACAAGTTAAAAGACAAGATGAAGACTATGATGAA
CAGGTCGAAGAGTCACTACAAGATGAGGATGATAATGATGTTTATATTCTGACCAAAGTG
TCAGATATTTTACACTCAATATTCAGTAGCTACAAAGAAAAGGTGTTACCATGGTTTGAA
CAGCTGCTTCCATTAATTGTCAACCTCATTTGTCCACATAGACCATGGCCAGACAGACAA
TGGGGATTATGCATCTTTGATGATGTCATAGAACACTGTAGTCCAGCCTCATTTAAATAC
GCAGAATATTTCTTAAGACCAATGCTCCAATATGTATGTGACAACAGCCCAGAAGTCAGG
CAAGCAGCTGCATATGGCCTGGGAGTCATGGCACAGTACGGTGGAGATAATTATCGCCCT
TTTTGTACAGAAGCACTTCCCCTGCTGGTAAGAGTTATTCAGTCTGCGGATTCTAAGACC
AAAGAAAATGTCAATGCTACAGAGAACTGCATCTCAGCAGTAGGGAAAATCATGAAGTTC
AAGCCTGACTGTGTAAACGTTGAAGAGGTCCTTCCACACTGGTTGTCTTGGCTTCCACTA
CATGAAGATAAAGAAGAAGCTGTTCAGACTTTCAATTATCTGTGTGACCTGATTGAAAGT
AATCATCCAATTGTTCTTGGCCCAAACAATACCAATCTGCCCAAAATATTTAGTATAATT
GCGGAAGGAGAAATGCACGAGGCAATTAAACATGAAGATCCTTGTGCCAAACGTCTGGCC
AATGTCGTTCGCCAAGTACAGACTTCTGGAGGACTGTGGACTGAGTGCATAGCACAGCTC
AGTCCTGAGCAGCAGGCCGCCATTCAGGAGCTCCTGAACTCTGCG
Restriction Sites Please inquire     
ACCN NM_002271
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002271.4, NP_002262.3
RefSeq Size 6019 bp
RefSeq ORF 3348 bp
Locus ID 3843
Cytogenetics 13q32.2
Protein Families Druggable Genome
Gene Summary 'Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.