APOL3 (NM_014349) Human Untagged Clone

CAT#: SC320945

APOL3 (untagged)-Human apolipoprotein L, 3 (APOL3), transcript variant alpha/a

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: APOL3
• Synonyms: apoL-III; APOLIII; CG12_1; CG121
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014349.2 AGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCACACTCTTTCAAGAGAAGCT
  TCCTTGGGTTAAGAAAAAAAACGAACCCTTCCAGTCAGGTCAGTGACTGGAGAGCTCCAA
  GGAAAGTCTCTCAGTGACCTGGCTGCTGGCACCATGGACTCAGAAAAGAAACGCTTTACT
  GAAGAGGCCACCAAATACTTCCGGGAGAGAGTCAGCCCAGTGCATCTGCAAATCCTGCTG
  ACTAACAATGAAGCCTGGAAGAGATTCGTGACTGCGGCTGAATTGCCCAGGGATGAGGCA
  GATGCTCTCTACGAAGCTCTGAAGAAGCTTAGAACATATGCAGCTATTGAGGACGAATAT
  GTGCAGCAGAAAGATGAGCAGTTTAGGGAATGGTTTTTGAAAGAGTTTCCCCAAGTCAAG
  AGGAAGATCCAGGAGTCCATAGAAAAGCTTCGTGCCCTTGCAAATGGTATTGAAGAGGTC
  CACAGAGGCTGCACCATCTCCAATGTGGTGTCCAGCTCCACTGGCGCTGCCTCTGGCATC
  ATGTCCCTTGCTGGTCTTGTTTTGGCACCATTTACAGCAGGGACGAGTCTGGCCCTTACT
  GCAGCTGGGGTAGGGCTGGGAGCAGCGTCTGCTGTGACTGGGATCACCACCAGCATCGTG
  GAGCACTCATACACATCATCAGCAGAAGCTGAAGCCAGCAGGCTGACTGCAACCAGCATT
  GACCGATTGAAGGTATTTAAGGAAGTTATGCGTGACATCACACCCAACTTACTTTCCCTT
  CTTAATAATTATTACGAAGCCACACAAACCATTGGGAGTGAAATCCGTGCCATCAGGCAA
  GCCAGAGCCAGGGCCCGACTCCCTGTGACCACCTGGCGAATCTCAGCTGGAAGTGGAGGT
  CAAGCAGAGAGAACGATTGCAGGCACCACCCGGGCAGTGAGCAGAGGAGCCCGGATCCTG
  AGTGCGACCACTTCAGGCATCTTCCTTGCACTGGATGTGGTCAACCTTGTATACGAGTCA
  AAGCACTTGCATGAGGGGGCAAAGTCTGCATCTGCTGAGGAGCTGAGGCGGCAGGCTCAG
  GAGCTGGAGGAGAATCTAATGGAGCTCACTCAGATCTATCAGCGTCTGAATCCATGCCAT
  ACCCACTGACCCCAGACCAGTGCAGCCAGCAGGGGAGGTGAGCCATACACAGGCCACGAC
  AAAATGCAGGCATTTTATTAGGGGGATAAAGAGGGCAAGGTAAAGTTTATGGAGCTGAGT
  GTTAGTGACTTTGGCATTTCTGTAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGC
  AAGTGCACCAAGGAGAAGGCAGGAATGCTGGAGCCTGGAATAAGGGAGGAGAGGGGACTG
  GAGAGTGTGGGGAATAGGAAGAAGAAATTTCCTTTAGACTAACGAATATATTGGGGGGAG
  GAATAGAGGGGAGGTGTGCAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAA
  AATGCAGAAAGCCGAAGAGTTAGAACTTTTGGATACAGCAGAAGAAACAGCGGCTCCACT
  ACCGACCTGCCCCCGGTTCGATGTCCTTCCAAGAATGAAGTCTTTCCCTGGTGATGGTCC
  CCTGCCCTGTCTTTCCAGCATCCACTCTGTCTTGTCCTCCTGGAAGTGTATCTCAGTCAG
  CCAGTGGCTTCTTGATGATGGCGGTGGAGGTGGTGGTTGTAGTGTGATGGATCCCCTTTA
  GGTTATTTAGGGGTATATGTCCCCTGCTTGAACCCTGAAGGCCAGGTAATGAGCCATGGC
  CATTGTCCCCAGCTGAGGACCAGGTGTCTCTAAAAACCCAAACATCCTGGAGAGTATGCG
  AGAACCTACCAAGAAAAACAGTCTCATTACTCATATACAGCAGGCAAAGAGACAGAAAAT
  TAACTGAAAAGCAGTTTAGAGACTGGGGGAGGCCGGATCTCTAGAGCCATCCTGCTGAGT
  GCCCTGTGTGTAAGTCCTAATAAACTCACCTACTCACCAAAAAAAAAAAAAAAAAAAAAA
  AAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014349.2 unedited
  GCGATTGTATACGACTCCTATAGGGCGGCGCGGATAATTCGGCACGAGGCTGTGTCCTAG
  TTGAGGCTAACAGTCAGTATCCAGCCTCAACATTCAGCAGAGGCCCCAGATCAGCGTCTG
  AGCCAGGCCAACAATGACCAAGGAGGATGGGATCCTGGGTGCAGCTCATCACAAGCGTCG
  GGGTGCAGCAAAACCATCCAGGCTGGACAGTGGCTGGACAGTTCCAAGAAAAGAAACGCT
  TCACTGAAGAAGTCATTGAATACTTCCAGAAGAAAGTTAGCCCAGTGCATCTGAAAATCC
  TGCTGACTAGCGATGAAGCCTGGAAGAGATTTGTTCGTGTGGCTGAATTGCCCAGGGAAG
  AGGCAGATGCTCTCTATGAAGCTCTGAAGAATCTTACACCATATGTGGCTATTGAGGACA
  AAGACATGCAGCAAAAAGAACAGCAGTTTAGGGAGTGGTTTTTGAAAGTTTCCTCAAATC
  AGATGGAAGATTCAGGAGTCCATAGAAAGGCTTCGTGTCATTGCAAATGAGATTGAAAAG
  GTCCACAGAGGCTGCGTCATCGCCAATGTGGTGTCTGGCTCCACTGGCATCCTGTCTGTC
  ATTGGCGTTATGTTGGCACCATTTACAGCAGGGCTGAGCCTGAGCATTACTGCAGCTGGG
  GTAGGGCTGGGAATAGCATCTGCCACGGCTGGGATCGCCTCCAGCATCGTGGAGAACACA
  TACACAAGGTCAGCAGAACTCACAGCCAGCAGCTGACTGCAACCAGCACTGACCAATTGG
  AGGCATTAAAGGACATTTCTGCGTGACATCACACCCAATGTGCTTTCTTTTGCACTTGAT
  TTGACGAAGCCACAAAAATGATGCGAATGATGTCATACACCTCAGGAGATCTAAGCCACT
  GTGACGCCTTTGATGCTGGCGATATGTACTATATGTTGTGGAACACTGAAAACACGTGGG
  GGCCCCCACCCGGATAGGTGGGCACT
• Restriction Sites: Please inquire
• ACCN: NM_014349
• ORF Size: 996 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014349.2, NP_055164.1
• RefSeq Size: 2444
• RefSeq ORF: 996
• Locus ID: 80833
• Gene Summary: This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
  Transcript Variant: This variant (alpha/a) differs in the coding region but maintains the reading frame compared to variant alpha/d. This variant encodes isoform 2, which is shorter and which contains a unique N-terminus compared to isoform 1.