Islet 1 (ISL1) (NM_002202) Human Untagged Clone

CAT#: SC322127

ISL1 (untagged)-Human ISL LIM homeobox 1 (ISL1)


  "NM_002202" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ISL1
Synonyms Isl-1; ISLET1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for SC322127 TGAAGGAAGAGGAAGAGGAGGAGAGGGAGGCCAGAGCCAGAACAGCCCGGCAGCCCGGGC
TTCGGGGGAGAACGGCCTGAGCCCCGAGCAAGTTGCCTCGGGAGCCCTAATCCTCTCCCG
CTGGCTCGCCGAGCGGTCAGTGGCGCTCAGCGGCGGCGAGGCTGAAATATGATAATCAGA
ACAGCTGCGCCGCGCGCCCTGCAGCCAATGGGCGCGGCGCTCGCCTGACGTCCCCGCGCG
CTGCGTCAGACCAATGGCGATGGAGCTGAGTTGGAGCAGAGAAGTTTGAGTAAGAGATAA
GGAAGAGAGGTGCCCGAGCCGCGCCGAGTCTGCCGCCGCCGCAGCGCCTCCGCTCCGCCA
ACTCCGCCGGCTTAAATTGGAATCCTAGATCCGCGAGGGCGCGGCGCAGCCGAGCAGCGG
CTCTTTCAGCATTGGCAACCCCAGGGGCCAATATTTCCCACTTAGCCACAGCTCCAGCAT
CCTCTCTGTGGGCTGTTCACCAGCTGTACAACCACCATTTCACTGTGGACATTACTCCCT
CTTACAGATATGGGAGACATGGGAGATCCACCAAAAAAAAAACGTCTGATTTCCCTATGT
GTTGGTTGCGGCAATCAGATTCACGATCAGTATATTCTGAGGGTTTCTCCGGATTTGGAA
TGGCATGCGGCATGTTTGAAATGTGCGGAGTGTAATCAGTATTTGGACGAGAGCTGTACA
TGCTTTGTTAGGGATGGGAAAACCTACTGTAAAAGAGATTATATCAGGTTGTACGGGATC
AAATGCGCCAAGTGCAGCATCGGCTTCAGCAAGAACGACTTCGTGATGCGTGCCCGCTCC
AAGGTGTATCACATCGAGTGTTTCCGCTGTGTGGCCTGCAGCCGCCAGCTCATCCCTGGG
GACGAATTTGCGCTTCGGGAGGACGGTCTCTTCTGCCGAGCAGACCACGATGTGGTGGAG
AGGGCCAGTCTAGGCGCTGGCGACCCGCTCAGTCCCCTGCATCCAGCGCGGCCACTGCAA
ATGGCAGCGGAGCCCATCTCCGCCAGGCAGCCGGCCCTGCGGCCCCACGTCCACAAGCAG
CCGGAGAAGACCACCCGCGTGCGGACTGTGCTGAACGAGAAGCAGCTGCACACCTTGCGG
ACCTGCTACGCCGCAAACCCGCGGCCAGATGCGCTCATGAAGGAGCAACTGGTAGAGATG
ACGGGCCTCAGTCCCCGTGTGATCCGGGTCTGGTTTCAAAACAAGCGGTGCAAGGACAAG
AAGCGAAGCATCATGATGAAGCAACTCCAGCAGCAGCAGCCCAATGACAAAACTAATATC
CAGGGGATGACAGGAACTCCCATGGTGGCTGCCAGTCCAGAGAGACACGACGGTGGCTTA
CAGGCTAACCCAGTGGAAGTACAAAGTTACCAGCCACCTTGGAAAGTACTGAGCGACTTC
GCCTTGCAGAGTGACATAGATCAGCCTGCTTTTCAGCAACTGGTCAATTTTTCAGAAGGA
GGACCGGGCTCTAATTCCACTGGCAGTGAAGTAGCATCAATGTCCTCTCAACTTCCAGAT
ACACCTAACAGCATGGTAGCCAGTCCTATTGAGGCATGAGGAACATTCATTCTGTATTTT
TTTTCCCTGTTGGAGAAAGTGGGAAATTATAATGTCGAACTCTGAAACAAAAGTATTTAA
CGACCCAGTCAATGAAAACTGAATCAAGAAATGAATGCTCCATGAAATGCACGAAGTCTG
TTTTAATGACAAGGTGATATGGTAGCAACACTGTGAAGACAATCATGGGATTTTACTAGA
ATTAAACAACAAACAAAACGCAAAACCCAGTATATGCTATTCAATGATCTTAGAAGTACT
GAAAAAAAAAGACGTTTTTAAAACGTAGAGGATTTATATTCAAGGATCTCAAAGAAAGCA
TTTTCATTTCACTGCACATCTAGAGAAAAACAAAAATAGAAAATTTTCTAGTCCATCCTA
ATCTGAATGGTGCTGTTTCTATATTGGTCATTGCCTTGCCAAACAGGAGCTCCAGCAAAA
GCGCAGGAAGAGAGACTGGCCTCCTTGGCTGAAAGAGTCCTTTCAGGAAGGTGGAGCTGC
ATTGGTTTGATATGTTTAAAGTTGACTTTAACAAGGGGTTAATTGAAATCCTGGGTCTCT
TGGCCTGTCCTGTAGCTGGTTTATTTTTTACTTTGCCCCCTCCCCACTTTTTTTGAGATC
CATCCTTTATCAAGAAGTCTGAAGCGACTTTAAAGGTTTTTGAATTCAGATTTAAAAACC
AACTTATAAAGCATTGCAACAAGGTTACCTCTATTTTGCCACAAGCGTCTCGGGATTGTG
TTTGACTTGTGTCTGTCCAAGAACTTTTCCCCCAAAGATGTGTATAGTTATTGGTTAAAA
TGACTGTTTTCTCTCTCTATGGAAATAAAAAGGAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_002202
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002202.2, NP_002193.2
RefSeq Size 2729 bp
RefSeq ORF 1050 bp
Locus ID 3670
Cytogenetics 5q11.1
Protein Families ES Cell Differentiation/IPS, Transcription Factors
Gene Summary 'This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]'

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