PABPC4 (NM_001135653) Human Untagged Clone

CAT#: SC325261

PABPC4 (untagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PABPC4
• Synonyms: APP-1; APP1; iPABP; PABP4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135653, the custom clone sequence may differ by one or more nucleotides
  ATGAACGCTGCGGCCAGCAGCTACCCCATGGCCTCCCTGTACGTGGGCGACCTGCATTCG
  GACGTCACCGAGGCCATGCTGTACGAAAAGTTCAGCCCCGCGGGGCCTGTGCTGTCCATC
  CGGGTCTGCCGCGATATGATCACCCGCCGCTCCCTGGGCTATGCCTACGTCAACTTCCAG
  CAGCCGGCCGACGCTGAGCGGGCTTTGGACACCATGAACTTTGATGTGATTAAGGGAAAG
  CCAATCCGCATCATGTGGTCTCAGAGGGATCCCTCTTTGAGAAAATCTGGTGTGGGAAAC
  GTCTTCATCAAGAACCTGGACAAATCTATAGATAACAAGGCACTTTATGATACTTTTTCT
  GCTTTTGGAAACATACTGTCCTGCAAGGTGGTGTGTGATGAGAACGGCTCTAAGGGTTAT
  GCCTTTGTCCACTTCGAGACCCAAGAGGCTGCCGACAAGGCCATCGAGAAGATGAATGGC
  ATGCTCCTCAATGACCGCAAAGTATTTGTGGGCAGATTCAAGTCTCGCAAAGAGCGGGAA
  GCTGAGCTTGGAGCCAAAGCCAAGGAATTCACCAATGTTTATATCAAAAACTTTGGGGAA
  GAGGTGGATGATGAGAGTCTGAAAGAGCTATTCAGTCAGTTTGGTAAGACCCTAAGTGTC
  AAGGTGATGAGAGATCCCAATGGGAAATCCAAAGGCTTTGGCTTTGTGAGTTACGAAAAA
  CACGAGGATGCCAATAAGGCTGTGGAAGAGATGAATGGAAAAGAAATAAGTGGTAAAATC
  ATATTTGTAGGCCGTGCACAAAAGAAAGTAGAACGGCAGGCAGAGTTAAAACGGAAATTT
  GAACAGTTGAAACAGGAGAGAATTAGTCGATATCAGGGGGTGAATCTCTACATTAAGAAC
  TTGGATGACACTATTGATGATGAGAAATTAAGGAAAGAATTTTCTCCTTTTGGATCAATT
  ACCAGTGCTAAGGTAATGCTGGAGGATGGAAGAAGCAAAGGGTTTGGCTTCGTCTGCTTC
  TCATCTCCTGAAGAAGCAACCAAAGCAGTCACTGAGATGAATGGACGCATTGTGGGCTCC
  AAGCCACTATATGTTGCCCTGGCCCAGAGGAAGGAAGAGAGAAAGGCTCACCTGACCAAC
  CAGTATATGCAACGAGTGGCTGGAATGAGAGCACTTCCTGCCAATGCCATCTTAAATCAG
  TTCCAGCCTGCAGCGGGTGGCTACTTTGTGCCAGCAGTCCCACAGGCTCAGGGAAGGCCT
  CCATATTATACACCTAACCAGTTAGCACAGATGAGGCCTAATCCACGCTGGCAGCAAGGT
  GGGAGACCTCAAGGCTTCCAAGGAATGCCAAGTGCTATACGCCAGTCTGGGCCTCGTCCA
  ACTCTTCGCCATCTGGCTCCAACTGGTAATGCTCCGGCCTCTCGTGGCCTCCCTACTACC
  ACTCAGAGAGTCGGGTCTGAGTGCCCGGACCGCTTGGCTATGGACTTTGGTGGGGCTGGT
  GCCGCCCAGCAAGGGCTGACTGACAGCTGCCAGTCTGGAGGCGTTCCCACAGCTGTGCAG
  AACTTAGCGCCACGCGCTGCTGTTGCTGCTGCTGCTCCCCGGGCTGTTGCCCCCTACAAA
  TACGCCTCCAGTGTCCGCAGCCCTCATCCTGCCATACAGCCTCTGCAGGCACCCCAGCCT
  GCGGTCCATGTGCAGGGGCAGGAGCCACTGACTGCCTCCATGCTGGCTGCAGCACCCCCC
  CAGGAACAGAAGCAGATGCTGGGAGAACGCTTGTTCCCACTCATCCAAACAATGCATTCA
  AATCTGGCTGGGAAGATCACGGGAATGCTGCTGGAGATAGACAACTCTGAGCTGCTGCAC
  ATGTTAGAGTCCCCCGAGTCTCTCCGCTCCAAGGTGGATGAAGCTGTAGCAGTTCTACAG
  GCTCATCATGCCAAGAAAGAAGCTGCCCAGAAGGTGGGCGCTGTTGCTGCTGCTACCTCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001135653
• ORF Size: 1983 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001135653.1, NP_001129125.1
• RefSeq Size: 3230
• RefSeq ORF: 1983
• Locus ID: 8761
• Gene Summary: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).