TRPC4 (NM_001135958) Human Untagged Clone

CAT#: SC326235

TRPC4 (untagged)-Human transient receptor potential cation channel, subfamily C, member 4 (TRPC4), transcript variant zeta

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPC4
• Synonyms: HTRP-4; HTRP4; TRP4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001135958, the custom clone sequence may differ by one or more nucleotides
  ATGGCTCAGTTCTATTACAAAAGAAATGTTAATGCTCCCTATAGAGACCGCATCCCTCTA
  AGGATAGTAAGAGCAGAATCAGAACTCTCGCCATCAGAAAAAGCCTACTTGAATGCTGTG
  GAAAAGGGAGATTATGCCAGTGTCAAGAAATCCCTAGAGGAAGCTGAAATTTATTTTAAA
  ATCAATATTAATTGCATTGATCCTCTCGGAAGAACTGCTCTCCTCATTGCAATTGAAAAT
  GAGAACTTGGAGCTCATCGAACTACTCTTAAGCTTTAATGTCTATGTTGGAGATGCTCTA
  TTACATGCTATCAGAAAAGAAGTCGTCGGAGCTGTTGAGCTGTTATTGAACCACAAAAAA
  CCTAGTGGAGAAAAACAGTTTGTTGCCCAGCCCAATTGTCAACAGCTGCTGGCATCTCGC
  TGGTACGATGAGTTTCCAGGCTGGAGGAGAAGACACTGGGCAGTGAAGATGGTGACATGT
  TTCATAATAGGACTTCTTTTTCCTGTCTTCTCTGTGTGCTACCTGATAGCTCCCAAAAGC
  CCACTTGGACTGTTCATCAGGAAGCCATTTATCAAGTTTATCTGCCACACAGCCTCCTAT
  TTGACTTTTTTGTTCCTGCTGCTGCTTGCCTCTCAGCACATCGACAGGTCAGACTTGAAC
  AGGCAAGGTCCACCACCAACCATCGTCGAGTGGATGATATTACCGTGGGTCCTGGGCTTC
  ATATGGGGAGAAATTAAACAGATGTGGGATGGCGGACTTCAGGACTACATCCATGATTGG
  TGGAATCTAATGGACTTTGTAATGAACTCCTTATATTTAGCAACAATCTCCTTGAAAATT
  GTTGCATTTGTAAAGTACAGTGCCCTTAATCCACGAGAATCATGGGACATGTGGCATCCC
  ACTCTGGTGGCAGAGGCTTTATTTGCTATTGCAAACATCTTCAGTTCTCTGCGTCTGATC
  TCACTGTTTACTGCAAATTCTCACCTGGGACCTCTGCAAATATCTCTGGGAAGAATGCTC
  CTGGACATTTTGAAGTTTCTATTCATATACTGCCTTGTGTTGCTAGCATTTGCAAATGGC
  CTAAATCAATTGTACTTCTATTATGAAGAAACGAAAGGGTTAACCTGCAAAGGCATAAGA
  TGTGAAAAGCAGAATAATGCATTTTCAACGTTATTTGAGACACTGCAGTCCCTGTTTTGG
  TCAATATTTGGGCTCATCAATTTATATGTGACCAATGTCAAAGCACAGCATGAATTTACT
  GAGTTTGTTGGTGCCACCATGTTTGGGACATACAATGTCATCTCTCTGGTTGTTCTACTC
  AACATGTTAATAGCTATGATGAATAATTCTTACCAACTGATTGCTGACCATGCAGATATA
  GAATGGAAATTTGCACGAACAAAGCTTTGGATGAGTTATTTTGAAGAAGGAGGTACTCTG
  CCTACTCCCTTCAATGTCATCCCGAGCCCCAAGTCTCTCTGGTACCTGATCAAATGGATC
  TGGACACACTTGTGCAAGAAAAAGATGAGAAGAAAGCCAGAAAGTTTTGGAACAATAGGG
  AGGCGAGCTGCTGATAACTTGAGAAGACATCACCAATACCAAGAAGTTATGAGGAACCTG
  GTGAAGCGATACGTTGCTGCAATGATTAGAGATGCTAAAACTGAAGAAGGCCTGACCGAA
  GAGAACTTTAAGGAACTAAAGCAAGACATTTCTAGTTTCCGCTTTGAAGTCCTGGGATTA
  CTAAGAGGAAGCAAACTTTCCACAATACAATCTGCGAATGCCTCGAAGGAGTCTTCAAAT
  TCGGCAGACTCAGATGAAAAGAGTGATAGCGAAGGTAATAGCAAGGACAAGAAAAAGAAT
  TTCAGCCTTTTTGATTTAACCACCCTGATTCATCCGAGATCAGCAGCAATTGCCTCTGAA
  AGACATAACATAAGCAATGGCTCTGCCCTGGTGGTTCAGGAGCCGCCCAGGGAGAAGCAG
  AGAAAAGTGAATTTTGTGACCGATATCAAAAACTTTGGGTTATTTCATAGACGATCAAAA
  CAAAATGCTGCTGAGCAAAATGCAAACCAAATCTTCTCTGTTTCAGAAGAAGTTGCTCGT
  CAACAGGCTGCAGGACCACTTGAGAGAAATATTCAACTGGAATCTCGAGGATTAGCTTCA
  CGGGGTGACCTGAGCATTCCCGGTCTCAGTGAACAATGTGTGTTAGTAGACCATAGAGAA
  AGGAATACGGACACACTGGGGTTACAGGTAGGAAAGAGAGTGTGTCCATTCAAGTCAGAG
  AAGGTGGTGGTGGAGGACACGGTTCCTATAATACCAAAGGAGAAACATGCAAAAGAAGAG
  GACTCTAGTATAGACTATGATCTAAACCTCCCAGACACAGTCACCCACGAAGATTACGTG
  ACCACAAGATTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001135958
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001135958.1, NP_001129430.1
• RefSeq Size: 3015 bp
• RefSeq ORF: 2415 bp
• Locus ID: 7223
• Cytogenetics: 13q13.3
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Gene Summary: 'This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]'
  Transcript Variant: This variant (6, also known as zeta) lacks an alternate in-frame segment in the 5' coding region, compared to variant 1 (alpha). The encoded isoform (zeta) is shorter, compared to isoform alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.