NFATC4 (NM_001136022) Human Untagged Clone

CAT#: SC326300

NFATC4 (untagged)-Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (NFATC4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFATC4
• Synonyms: NF-AT3; NF-ATC4; NFAT3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001136022 edited
  GCCACCATGATAACCACCCTCCCATCTCTCCTACCCGCCAGCCTCGCCAGTATCTCCCAC
  CGAGTCACGAATCTCCCATCTAACTCCCTCTCACACAACCCAGGCCTCTCCAAGCCTGAC
  TTTCCCGGAAACTCCAGTCCAGGTCTTCCTTCCTCCTCCAGCCCAGGCCGGGACCTGGGG
  GCTCCTGCCGGATCCATGGGGGCGGCCAGCTGCGAGGATGAGGAGCTGGAATTTAAGCTG
  GTGTTCGGGGAGGAAAAGGAGGCCCCCCCGCTGGGCGCGGGGGGATTGGGGGAAGAACTG
  GACTCAGAGGATGCCCCGCCATGCTGCCGTCTGGCCTTGGGAGAGCCCCCTCCCTATGGC
  GCTGCACCTATCGGTATTCCCCGACCTCCACCCCCTCGGCCTGGCATGCATTCGCCACCG
  CCGCGACCAGCCCCCTCACCTGGCACCTGGGAGAGCCAGCCCGCCAGGTCGGTGAGGCTG
  GGAGGACCAGGAGGGGGTGCTGGGGGTGCTGGGGGTGGCCGTGTTCTCGAGTGTCCCAGC
  ATCCGCATCACCTCCATCTCTCCCACGCCGGAGCCGCCAGCAGCGCTGGAGGACAACCCT
  GATGCCTGGGGGGACGGCTCTCCTAGAGATTACCCCCCACCAGAAGGCTTTGGGGGCTAC
  AGAGAAGCAGGGGGCCAGGGTGGGGGGGCCTTCTTCAGCCCAAGCCCTGGCAGCAGCAGC
  CTGTCCTCGTGGAGCTTCTTCTCCGATGCCTCTGACGAGGCAGCCCTGTATGCAGCCTGC
  GACGAGGTGGAGTCTGAGCTAAATGAGGCGGCCTCCCGCTTTGGCCTGGGCTCCCCGCTG
  CCCTCGCCCCGGGCCTCCCCTCGGCCATGGACCCCCGAAGATCCCTGGAGCCTGTATGGT
  CCAAGCCCCGGAGGCCGAGGGCCAGAGGATAGCTGGCTACTCCTCAGTGCTCCTGGGCCC
  ACCCCAGCCTCCCCGCGGCCTGCCTCTCCATGTGGCAAGCGGCGCTATTCCAGCTCGGGA
  ACCCCATCTTCAGCCTCCCCAGCTCTGTCCCGCCGTGGCAGCCTGGGGGAAGAGGGGTCT
  GAGCCACCTCCACCACCCCCATTGCCTCTGGCCCGGGACCCGGGCTCCCCTGGTCCCTTT
  GACTATGTGGGGGCCCCACCAGCTGAGAGCATCCCTCAGAAGACACGGCGGACTTCCAGC
  GAGCAGGCAGTGGCTCTGCCTCGGTCTGAGGAGCCTGCCTCATGCAATGGGAAGCTGCCC
  TTGGGAGCAGAGGAGTCTGTGGCTCCTCCAGGAGGTTCCCGGAAGGAGGTGGCTGGCATG
  GACTACCTGGCAGTGCCCTCCCCACTCGCTTGGTCCAAGGCCCGGATTGGGGGACACAGC
  CCTATCTTCAGGACCTCTGCCCTACCCCCACTGGACTGGCCTCTGCCCAGCCAATATGAG
  CAGCTGGAGCTGAGGATCGAGGTACAGCCTAGAGCCCACCACCGGGCCCACTATGAGACA
  GAAGGCAGCCGTGGAGCTGTCAAAGCTGCCCCTGGCGGTCACCCCGTAGTCAAGCTCCTA
  GGCTACAGTGAGAAGCCACTGACCCTACAGATGTTCATCGGCACTGCAGATGAAAGGAAC
  CTGCGGCCTCATGCCTTCTATCAGGTGCACCGTATCACAGGCAAGATGGTGGCCACGGCC
  AGCTATGAAGCCGTAGTCAGTGGCACCAAGGTGTTGGAGATGACTCTGCTGCCTGAGAAC
  AACATGGCGGCCAACATTGACTGCGCGGGAATCCTGAAGCTTCGGAATTCAGACATTGAG
  CTTCGGAAGGGTGAGACGGACATCGGGCGCAAAAACACACGTGTACGGCTGGTGTTCCGG
  GTACACGTGCCCCAGGGCGGCGGGAAGGTCGTCTCAGTACAGGCAGCATCGGTGCCCATC
  GAGTGCTCCCAGCGCTCAGCCCAGGAGCTGCCCCAGGTGGAGGCCTACAGCCCCAGTGCC
  TGCTCTGTGAGAGGAGGCGAGGAACTGGTACTGACTGGCTCCAACTTCCTGCCAGACTCC
  AAGGTGGTGTTCATTGAGAGGGGTCCTGATGGGAAGCTGCAATGGGAGGAGGAGGCCACA
  GTGAACCGACTGCAGAGCAACGAGGTGACGCTGACCCTGACTGTCCCCGAGTACAGCAAC
  AAGAGGGTTTCCCGGCCAGTCCAGGTCTACTTTTATGTCTCCAATGGGCGGAGGAAACGC
  AGTCCTACCCAGAGTTTCAGGTTTCTGCCTGTGATCTGCAAAGAGGAGCCCCTACCGGAC
  TCATCTCTGCGGGGTTTCCCTTCAGCATCGGCAACCCCCTTTGGCACTGACATGGACTTC
  TCACCACCCAGGCCCCCCTACCCCTCCTATCCCCATGAAGACCCTGCTTGCGAAACTCCT
  TACCTATCAGAAGGCTTCGGCTATGGCATGCCCCCTCTGTACCCCCAGACGGGGCCCCCA
  CCATCCTACAGACCGGGCCTGCGGATGTTCCCTGAGACTAGGGGTACCACAGGTTGTGCC
  CAACCACCTGCAGTTTCCTTCCTTCCCCGCCCCTTCCCTAGTGACCCGTATGGAGGGCGG
  GGCTCCTCTTTCTCCCTGGGGCTGCCATTCTCTCCGCCAGCCCCCTTTCGGCCGCCTCCT
  CTTCCTGCATCCCCACCGCTTGAAGGCCCCTTCCCTTCCCAGAGTGATGTGCATCCCCTA
  CCTGCTGAGGGATACAATAAGGTAGGGCCAGGCTATGGCCCTGGGGAGGGGGCTCCGGAG
  CAGGAGAAATCCAGGGGTGGCTACAGCAGCGGCTTCCGAGACAGTGTCCCTATCCAGGGT
  ATCACGCTGGAGGAAGGTGGGTGTGGGACTGGGGGCTGTGAGTGTGAGTGTGTGCAAGAG
  ATTGCTCTGCATGTTTGCTGAGGGCTGGAGCTGGGCTTTTCAGAGATCGGGCATCCCTGG
  TCTCTCAGGGCCAGTTGGAGGTTCCCAGGAGGCATGTTCTTGATGCCTGTGGCTGCCTGA
  ATCCAATTAACTGAATTCTGAAGAGTGCATGGGGTAACTGTCTCAGCCTTTCTCCTGTCT
  CTGCCTCTGTCCTCTGCTCCAAATCATAAAATCTCAGAGCTAGAAGCACTTTCAAGATCA
  TTCCATCCAGCGCATTCAATTTGCAAGTTTAGGCGTTGAGTTCCAGAGAGGGATGGTAGC
  TTGCTGAGGTCCCAGTCAAGCACACTTGCCATTGCCTCAGCTTTCCCCTAAACACGGTGT
  CTGTGGTCAGGGTTGGTGAGGAGGAGCTTTCCTGTTTTGCCTCTCCTTCTTCCCATTGGC
  TACACCCATCTCTGGCCCTGCTGATACCGATTCCCCTGACATTTCAGGCTAAGCCAGCAG
  GAAAGGGCTAGGACGGGTGCCTGGGAGCCCACATGGAGGGAGTTGGGCAAGATTTGATTC
  GGAGCAGGTGTCAAGACGTGTTGGGGAAACTGAGGCCCAGTGGAATAGAAGCCAGTAGAG
  GAGGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001136022
• Insert Size: 4600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001136022.1, NP_001129494.1
• RefSeq Size: 5672 bp
• RefSeq ORF: 2895 bp
• Locus ID: 4776
• Cytogenetics: 14q12
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: 'This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes isoform (1).