HSPC302 (TBCK) (NM_001163437) Human Untagged Clone

CAT#: SC327664

TBCK (untagged)-Human TBC1 domain containing kinase (TBCK) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TBCK
• Synonyms: HSPC302; IHPRF3; TBCKL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001163437, the custom clone sequence may differ by one or more nucleotides
  ATGTTTCCCCTGAAGGACGCTGAAATGGGAGCCTTTACCTTCTTTGCCTCGGCTCTGCCA
  CATGATGTTTGTGGAAGCAATGGACTTCCTCTCACACCAAATTCCATCAAAATTTTAGGG
  CGCTTTCAAATCCTTAAAACCATCACCCATCCCAGACTCTGCCAGTATGTGGATATTTCT
  AGGGGAAAGCATGAACGACTAGTGGTCGTGGCTGAACATTGTGAACGTAGTCTGGAAGAC
  TTGCTTCGAGAAAGGAAACCTGTGAGCTGTTCAACGGTTTTGTGTATAGCATTTGAGGTT
  CTTCAGGGCTTGCAGTATATGAACAAACATGGTATAGTACACAGGGCATTGTCTCCTCAT
  AATATCCTGTTGGACCGAAAGGGACATATTAAATTGGCTAAATTTGGACTTTATCACATG
  ACAGCTCATGGTGATGATGTTGATTTCCCAATAGGGTATCCCTCGTACTTGGCCCCTGAG
  GGAAGAAAATTATTTCAGAGCTTGGATATTTCTGAAAGACTAAAATTTTTGCTTACTTTG
  GATTGTGTAGATGACACTTTAATAGTTCTGGCTGAAGAGCATGGTTGTTTGGACATTATA
  AAGGAGCTTCCTGAAACTGTGATAGATCTTTTGAATAAGTGCCTTACCTTCCATCCTTCT
  AAGAGGCCAACCCCAGATGAATTAATGAAGGACAAAGTATTCAGTGAGGTATCACCTTTA
  TATACCCCCTTTACCAAACCTGCCAGTCTGTTTTCATCTTCTCTGAGATGTGCTGATTTA
  ACTCTGCCTGAGGATATCAGTCAGTTGTGTAAAGATATAAATAATGATTACCTGGCAGAA
  AGATCTATTGAAGAAGTGTATTACCTTTGGTGTTTGGCTGGAGGTGACTTGGAGAAAGAG
  CTTGTCAACAAGGAAATCATTCGATCCAAACCACCTATCTGCACACTCCCCAATTTTCTC
  TTTGAGGATGGTGAAAGCTTTGGACAAGGTCGAGATAGAAGCTCGCTTTTAGATGATACC
  ACTGTGACATTGTCGTTATGCCAGCTAAGAAATAGATTGAAAGATGTTGGTGGAGAAGCA
  TTTTACCCATTACTTGAAGATGACCAGTCTAATTTACCTCATTCAAACAGCAATAATGAG
  TTGTCTGCAGCTGCCACGCTCCCTTTAATCATCAGAGAGAAGGATACAGAGTACCAACTA
  AATAGAATTATTCTCTTCGACAGGCTGCTAAAGGCTTATCCATATAAAAAAAACCAAATC
  TGGAAAGAAGCAAGAGTTGACATTCCTCCTCTTATGAGAGGTTTAACCTGGGCTGCTCTT
  CTGGGAGTTGAGGGAGCTATTCATGCCAAGTACGATGCAATTGATAAAGACACTCCAATT
  CCTACAGATAGACAAATTGAAGTGGATATTCCTCGCTGTCATCAGTACGATGAACTGTTA
  TCATCACCAGAAGGTCATGCAAAATTTAGGCGTGTATTAAAAGCCTGGGTAGTGTCTCAT
  CCTGATCTTGTGTATTGGCAAGGTCTTGACTCACTTTGTGCTCCATTCCTATATCTAAAC
  TTCAATAATGAAGCCTTGGCTTATGCATGTATGTCTGCTTTTATTCCCAAATACCTGTAT
  AACTTCTTCTTAAAAGACAACTCACATGTAATACAAGAGTATCTGACTGTCTTCTCTCAG
  ATGATTGCATTTCATGATCCAGAGCTGAGTAATCATCTCAATGAGATTGGTTTCATTCCA
  GATCTCTATGCCATCCCTTGGTTTCTTACCATGTTTACTCATGTATTTCCACTACACAAA
  ATTTTCCACCTCTGGGATACCTTACTACTTGGGAATTCCTCTTTCCCATTCTGTATTGGA
  GTAGCAATTCTTCAGCAGCTGCGGGACCGGCTTTTGGCTAATGGCTTTAATGAGTGTATT
  CTTCTCTTCTCCGATTTACCAGAAATTGACATTGAACGCTGTGTGAGAGAATCTATCAAC
  CTGTTTTGTTGGACTCCTAAAAGTGCTACTTACAGACAGCATGCTCAACCTCCAAAGCCA
  TCTTCTGACAGCAGTGGAGGCAGAAGTTCGGCACCTTATTTCTCTGCTGAGTGTCCAGAT
  CCTCCAAAGACAGATCTGTCAAGAGAATCCATCCCATTAAATGACCTGAAGTCAGAAGTA
  TCACCACGGATTTCAGCAGAGGACCTGATTGACTTGTGTGAGCTCACAGTGACAGGCCAC
  TTCAAAACACCCAGCAAGAAAACAAAGTCCAGTAAACCAAAGCTCCTGGTGGTTGACATC
  CGGAATAGTGAAGACTTTATTCGTGGTCACATTTCAGGAAGCATCAACATTCCATTCAGT
  GCTGCCTTCACTGCAGAAGGGGAGCTTACCCAGGGCCCTTACACTGCTATGCTCCAGAAC
  TTCAAAGGGAAGGTCATTGTCATCGTGGGGCATGTGGCAAAACACACAGCTGAGTTTGCA
  GCTCACCTTGTGAAGATGAAATATCCAAGAATCTGTATTCTAGATGGTGGCATTAATAAA
  ATAAAGCCAACAGGCCTCCTCACCATCCCATCTCCTCAAATA
  
• Restriction Sites: Please inquire
• ACCN: NM_001163437
• ORF Size: 2565 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001163437.1, NP_001156909.1
• RefSeq Size: 3424
• RefSeq ORF: 2565
• Locus ID: 93627
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. This results in a shorter protein (isoform b) compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.