Neogenin (NEO1) (NM_001172623) Human Untagged Clone

CAT#: SC329351

NEO1 (untagged)-Human neogenin homolog 1 (chicken) (NEO1) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NEO1
• Synonyms: IGDCC2; NGN; NTN1R2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172623, the custom clone sequence may differ by one or more nucleotides
  ATGGCGGCGGAGCGGGGAGCCCGGCGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGC
  CTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCCGCGCCG
  CAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTG
  GATACACTCTCAGTTAGAGGCTCTTCTGTTATATTAAACTGTTCAGCATATTCTGAGCCT
  TCTCCAAAAATTGAATGGAAAAAAGATGGAACTTTTTTAAACTTAGTATCAGATGATCGA
  CGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAAT
  AAACCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATC
  AGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCAGAACCT
  TCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTC
  CCATTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAA
  CTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTTTATCGC
  TGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTT
  CCAGATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGA
  GTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCAACCATT
  AAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTG
  GCAGGTGGTAGCCTGGAGATCAGTGATGTTACTGAGGATGATGCTGGGACTTATTTTTGT
  ATAGCTGATAATGGAAATGAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAAGCTCAA
  CCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTT
  GAATGTGAAGTGACTGGAAAACCAACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATG
  GTTATCCCAAGTGATTATTTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTGGGTCTG
  GTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAA
  GCTGGAGCCCAACTGATAATCCTTGAACATGCACCAGCCACAACGGGACCACTGCCTTCA
  GCTCCTCGGGATGTCGTGGCCTCCCTGGTCTCTACCCGCTTCATCAAATTGACGTGGCGG
  ACACCTGCATCAGATCCTCACGGAGACAACCTTACCTACTCTGTGTTCTACACCAAGGAA
  GGGATTGCTAGGGAACGTGTTGAGAATACCAGTCACCCAGGAGAGATGCAAGTAACCATT
  CAAAACCTAATGCCAGCGACCGTGTACATCTTTAGAGTTATGGCTCAAAATAAGCATGGC
  TCAGGAGAGAGTTCAGCTCCACTGCGAGTAGAAACACAACCTGAGGTTCAGCTCCCTGGC
  CCAGCACCTAACCTTCGTGCATATGCAGCTTCGCCTACCTCCATCACTGTTACGTGGGAA
  ACACCAGTGTCTGGCAATGGGGAAATTCAGAATTATAAATTGTACTACATGGAAAAGGGG
  ACTGATAAAGAACAGGATGTTGATGTTTCAAGTCACTCTTACACCATTAATGGGTTGAAA
  AAATATACAGAGTATAGTTTCCGAGTGGTGGCCTACAATAAACATGGTCCTGGAGTTTCC
  ACACCAGATGTTGCTGTTCGAACATTGTCAGATGTTCCCAGTGCTGCTCCTCAGAATCTG
  TCCTTGGAAGTGAGAAATTCAAAGAGTATTATGATTCACTGGCAGCCACCTGCTCCAGCC
  ACACAAAATGGGCAGATTACTGGCTACAAGATTCGCTACCGAAAGGCCTCCCGAAAGAGT
  GATGTCACTGAGACCTTGGTAAGCGGGACACAGCTGTCTCAGCTGATTGAAGGTCTTGAT
  CGGGGGACTGAGTATAATTTCCGAGTGGCTGCTCTAACAATCAATGGTACAGGCCCGGCA
  ACTGACTGGCTGTCTGCTGAAACTTTTGAAAGTGACCTAGATGAAACTCGTGTTCCTGAA
  GTGCCTAGCTCTCTTCACGTACGCCCGCTCGTTACTAGCATCGTAGTGAGCTGGACTCCT
  CCAGAGAATCAGAACATTGTGGTCAGAGGTTACGCCATTGGTTATGGCATTGGCAGCCCT
  CATGCCCAGACCATCAAAGTGGACTATAAACAGCGCTATTACACCATTGAAAATCTGGAT
  CCCAGCTCTCACTATGTGATTACCCTGAAAGCATTTAATAACGTGGGTGAAGGCATCCCC
  CTGTATGAGAGTGCTGTGACCAGGCCTCACACAGACACTTCTGAAGTTGATTTATTTGTT
  ATTAATGCTCCATACACTCCAGTGCCAGATCCCACTCCCATGATGCCACCAGTGGGAGTT
  CAGGCTTCCATTCTGAGTCATGACACCATCAGGATTACGTGGGCAGACAACTCGCTGCCC
  AAGCACCAGAAGATTACAGACTCCCGATACTACACCGTCCGATGGAAAACCAACATCCCA
  GCAAACACCAAGTACAAGAATGCAAATGCAACCACTTTGAGTTATTTGGTGACTGGTTTA
  AAGCCGAATACACTCTATGAATTCTCTGTGATGGTGACCAAAGGTCGAAGATCAAGTACA
  TGGAGTATGACAGCCCATGGGACCACCTTTGAATTAGTTCCGACTTCTCCACCCAAGGAT
  GTGACTGTTGTGAGTAAAGAGGGGAAACCTAAGACCATAATTGTGAATTGGCAGCCTCCC
  TCCGAAGCCAATGGCAAAATTACAGGTTACATCATATATTACAGTACAGATGTGAATGCA
  GAGATACATGACTGGGTTATTGAGCCTGTTGTGGGAAACAGACTGACTCACCAGATACAA
  GAGTTAACTCTTGACACACCATACTACTTCAAAATCCAGGCACGGAACTCAAAGGGCATG
  GGACCCATGTCTGAAGCTGTCCAATTCAGAACACCTAAAGCGGACTCCTCTGATAAAATG
  CCTAATGATCAAGCCTCAGGGTCTGGAGGGAAAGGAAGCCGGCTGCCAGACCTAGGATCC
  GACTACAAACCTCCAATGAGCGGCAGTAACAGCCCTCATGGGAGCCCCACCTCTCCTCTG
  GACAGTAATATGCTGCTGGTCATAATTGTTTCTGTTGGCGTCATCACCATCGTGGTGGTT
  GTGATTATCGCTGTCTTTTGTACCCGTCGTACCACCTCTCACCAGAAAAAGAAACGAGCT
  GCCTGCAAATCAGTGAATGGCTCTCATAAGTACAAAGGGAATTCCAAAGATGTGAAACCT
  CCAGATCTCTGGATCCATCATGAGAGACTGGAGCTGAAACCCATTGATAAGTCTCCAGAC
  CCAAACCCCATCATGACTGATACTCCAATTCCTCGCAACTCTCAAGATATCACACCAGTT
  GACAACTCCATGGACAGCAATATCCATCAAAGGCGAAATTCATACAGAGGGCATGAGTCA
  GAGGACAGCATGTCTACACTGGCTGGAAGGCGAGGAATGAGACCAAAAATGATGATGCCC
  TTTGACTCCCAGCCACCCCAGCAATCCGTTCGAAATACCCCCAGCACTGACACCATGCCA
  GCCTCTTCGTCTCAAACATGCTGCACTGATCACCAGGACCCTGAAGGTGCTACCAGCTCC
  TCTTACTTGGCCAGCTCCCAAGAGGAAGATTCAGGCCAGAGTCTTCCCACTGCCCATGTT
  CGCCCTTCCCACCCATTGAAGAGCTTCGCCGTGCCAGCAATCCCGCCTCCAGGACCTCCC
  ACCTATGATCCTGCATTGCCAAGCACACCATTACTGTCCCAGCAAGCTCTGAACCATCAC
  ATTCACTCAGTGAAGACAGCCTCCATCGGGACTCTAGGAAGGAGCCGGCCTCCTATGCCA
  GTGGTTGTTCCCAGTGCCCCTGAAGTGCAGGAGACCACAAGGATGTTGGAAGACTCCGAG
  AGTAGCTATGAACCAGATGAGCTGACCAAAGAGATGGCCCACCTGGAAGGACTAATGAAG
  GACCTAAACGCTATCACAACAGCATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001172623
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001172623.1, NP_001166094.1
• RefSeq Size: 6929 bp
• RefSeq ORF: 4227 bp
• Locus ID: 4756
• Cytogenetics: 15q24.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: 'This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]'
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.