PMPCA (NM_001282944) Human Untagged Clone

CAT#: SC335842

PMPCA (untagged) - Human peptidase (mitochondrial processing) alpha (PMPCA), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PMPCA
• Synonyms: Alpha-MPP; CLA1; CPD3; INPP5E; P-55; SCAR2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282944, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCGAAATACCTTAGTGGAATTGCTCACTTTTTGGAAAAATTGGCATTTTCGTCTACTGCTCGATT
  TGACAGCAAAGATGAAATTCTGCTTACGTTGGAAAAGCATGGGGGTATCTGTGACTGCCAGACATCAAGA
  TGAAGAAGTCGAGATGACGCGGATGGCGGTCCAGTTTGAGCTGGAGGACCTGAACCTGCGGCCTGACCCA
  GAGCCACTTCTCACCGAGATGATTCATGAAGCGGCTTACAGGGAGAACACAGTTGGCCTCCACCGTTTCT
  GCCCCACAGAAAACGTAGCAAAGATCAACCGAGAGGTGCTGCATTCCTACCTGAGGAACTACTACACTCC
  CGACCGCATGGTGCTGGCCGGCGTGGGCGTGGAGCACGAGCATCTGGTGGACTGTGCCCGGAAGTACCTC
  CTGGGGGTCCAGCCGGCCTGGGGGAGCGCAGAGGCCGTGGATATTGACAGATCTGTGGCCCAGTACACTG
  GGGGGATTGCCAAGCTAGAAAGAGACATGTCCAATGTCAGCCTGGGCCCGACCCCCATCCCCGAGCTCAC
  GCACATCATGGTTGGACTGGAGAGCTGCTCCTTCCTGGAGGAGGACTTCATCCCCTTTGCAGTGTTGAAC
  ATGATGATGGGCGGAGGTGGCTCCTTCTCGGCTGGTGGGCCCGGCAAGGGCATGTTCTCCAGGCTCTACC
  TCAACGTGCTCAACAGGCACCACTGGATGTATAACGCGACCTCCTACCACCACAGCTACGAGGACACTGG
  CCTCCTTTGCATCCATGCCAGCGCCGACCCAAGACAGGTTCGAGAAATGGTAGAAATCATCACAAAGGAG
  TTTATTTTAATGGGCGGAACCGTGGACACGGTGGAGCTGGAACGAGCCAAGACGCAGCTGACATCAATGC
  TCATGATGAACCTGGAATCCAGGCCTGTGATCTTCGAGGATGTGGGGAGGCAGGTGCTGGCCACTCGCTC
  CAGAAAGCTGCCGCACGAGCTGTGCACGCTCATCCGCAACGTGAAGCCGGAAGATGTGAAGAGAGTCGCT
  TCTAAGATGCTCCGAGGGAAGCCGGCAGTGGCCGCCCTGGGTGACCTGACTGACCTGCCCACGTATGAGC
  ACATCCAGACCGCCCTGTCGAGTAAGGACGGGCGCCTGCCCAGGACGTACCGGCTCTTCCGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282944
• ORF Size: 1185 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282944.1, NP_001269873.1
• RefSeq Size: 2087
• RefSeq ORF: 1185
• Locus ID: 23203
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) lacks an exon in the 5' coding region which results in the use of a alternate start codon compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.