TIGIT (NM_173799) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221447L1V

Lenti ORF particles, TIGIT (Myc-DDK tagged) - Human T cell immunoreceptor with Ig and ITIM domains (TIGIT), 200ul, >10^7 TU/mL

Product Images

RC221447L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC221447L1V particle to overexpress human TIGIT-Myc-DDK fusion protein.

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  RC221447L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC221447L1V particle to overexpress human TIGIT-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TIGIT
• Synonyms: VSIG9; VSTM3; WUCAM
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_173799
• ORF Size: 732 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221447).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_173799.2
• RefSeq Size: 2978 bp
• RefSeq ORF: 735 bp
• Locus ID: 201633
• UniProt ID: Q495A1
• Cytogenetics: 3q13.31
• Protein Families: Transmembrane
• MW: 26.3 kDa
• Gene Summary: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]