HS2ST1 (NM_012262) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223657L1V

Lenti ORF particles, HS2ST1 (Myc-DDK tagged) - Human heparan sulfate 2-O-sulfotransferase 1 (HS2ST1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: HS2ST1
• Synonyms: dJ604K5.2
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_012262
• ORF Size: 1068 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223657).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_012262.2, NP_036394.1
• RefSeq Size: 6708
• RefSeq ORF: 1071
• Locus ID: 9653
• Domains: HS2ST
• Protein Pathways: Heparan sulfate biosynthesis
• MW: 41.7 kDa
• Gene Summary: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]