PPAR delta (PPARD) (NM_001171820) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC229912L3V

  • LentiORF®

Lenti ORF particles, PPARD (Myc-DDK tagged) - Human peroxisome proliferator-activated receptor delta (PPARD), transcript variant 5, 200ul, >10^7 TU/mL

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USD 820.00

6 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol PPARD
Synonyms FAAR; NR1C2; NUC1; NUCI; NUCII; PPARB
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_001171820
ORF Size 1029 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC229912).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001171820.1, NP_001165291.1
RefSeq ORF 1032 bp
Locus ID 5467
Cytogenetics 6p21.31
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Acute myeloid leukemia, Pathways in cancer, PPAR signaling pathway, Wnt signaling pathway
MW 39.3 kDa
Gene Summary 'This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]'

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