Human FGF1 activation kit by CRISPRa

CAT#: GA101569

FGF1 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGF1
• Locus ID: 2246
• Kit Components:

  GA101569G1, FGF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101569G2, FGF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101569G3, FGF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000800, NM_001144892, NM_001144934, NM_001144935, NM_001257205, NM_001257206, NM_001257207, NM_001257208, NM_001257209, NM_001257210, NM_001257211, NM_001257212, NM_033136, NM_033137, NR_026695, NR_026696, NM_001354951, NM_001354952, NM_001354953, NM_001354954, NM_001354955, NM_001354956, NM_001354957, NM_001354958, NM_001354959, NM_001354961, NM_001354962, NM_001354963, NM_001354964
• Synonyms: AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]'