FGF1 Human Gene Knockout Kit (CRISPR)

CAT#: KN407434

FGF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: FGF1
• Locus ID: 2246
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_000800, NM_001144892, NM_001144934, NM_001144935, NM_001257205, NM_001257206, NM_001257207, NM_001257208, NM_001257209, NM_001257210, NM_001257211, NM_001257212, NM_033136, NM_033137, NR_026695, NR_026696, NM_001354951, NM_001354952, NM_001354953, NM_001354954, NM_001354955, NM_001354956, NM_001354957, NM_001354958, NM_001354959, NM_001354961, NM_001354962, NM_001354963, NM_001354964
• Synonyms: AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]'