Human FGL1 activation kit by CRISPRa

CAT#: GA101589

FGL1 CRISPRa kit - CRISPR gene activation of human fibrinogen like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGL1
• Locus ID: 2267
• Kit Components:

  GA101589G1, FGL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101589G2, FGL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101589G3, FGL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004467, NM_147203, NM_201552, NM_201553
• Synonyms: HFREP1; HP-041; LFIRE-1; LFIRE1
• Summary: 'Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]'