Human BLOC1S1 activation kit by CRISPRa

CAT#: GA101766

BLOC1S1 CRISPRa kit - CRISPR gene activation of human biogenesis of lysosomal organelles complex 1 subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BLOC1S1
• Locus ID: 2647
• Kit Components:

  GA101766G1, BLOC1S1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101766G2, BLOC1S1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101766G3, BLOC1S1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001487, NR_037655, NR_037656, NR_037657
• Synonyms: BLOS1; GCN5L1; MICoA; RT14
• Summary: 'BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM, Mar 2008]'