Human GPLD1 activation kit by CRISPRa

CAT#: GA101887

GPLD1 CRISPRa kit - CRISPR gene activation of human glycosylphosphatidylinositol specific phospholipase D1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPLD1
• Locus ID: 2822
• Kit Components:

  GA101887G1, GPLD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101887G2, GPLD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101887G3, GPLD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001503, NM_177483
• Synonyms: GPIPLD; GPIPLDM; PIGPLD; PIGPLD1; PLD
• Summary: 'Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]'