Human KCNK3 activation kit by CRISPRa

CAT#: GA102551

KCNK3 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK3
• Locus ID: 3777
• Kit Components:

  GA102551G1, KCNK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102551G2, KCNK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102551G3, KCNK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002246
• Synonyms: K2p3.1; OAT1; PPH4; TASK; TASK-1; TBAK1
• Summary: 'This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]'