Human NPPC activation kit by CRISPRa

CAT#: GA103257

NPPC CRISPRa kit - CRISPR gene activation of human natriuretic peptide C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPPC
• Locus ID: 4880
• Kit Components:

  GA103257G1, NPPC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103257G2, NPPC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103257G3, NPPC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024409
• Synonyms: CNP; CNP2
• Summary: 'This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]'