Human P2Y1 (P2RY1) activation kit by CRISPRa

CAT#: GA103357

P2RY1 CRISPRa kit - CRISPR gene activation of human purinergic receptor P2Y1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P2RY1
• Locus ID: 5028
• Kit Components:

  GA103357G1, P2Y1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103357G2, P2Y1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103357G3, P2Y1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002563
• Synonyms: P2Y1
• Summary: 'The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]'