Human PLRG1 activation kit by CRISPRa

CAT#: GA103614

PLRG1 CRISPRa kit - CRISPR gene activation of human pleiotropic regulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLRG1
• Locus ID: 5356
• Kit Components:

  GA103614G1, PLRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103614G2, PLRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103614G3, PLRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201564, NM_002669
• Synonyms: Cwc1; PRL1; PRP46; PRPF46; TANGO4
• Summary: 'This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]'