Human MKRN3 activation kit by CRISPRa

CAT#: GA105250

MKRN3 CRISPRa kit - CRISPR gene activation of human makorin ring finger protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MKRN3
• Locus ID: 7681
• Kit Components:

  GA105250G1, MKRN3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105250G2, MKRN3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105250G3, MKRN3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005664
• Synonyms: CPPB2; D15S9; RNF63; ZFP127; ZNF127
• Summary: 'The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]'