Human Hephaestin (HEPH) activation kit by CRISPRa

CAT#: GA106636

HEPH CRISPRa kit - CRISPR gene activation of human hephaestin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HEPH
• Locus ID: 9843
• Kit Components:

  GA106636G1, HEPH gRNA vector 1 in pCas-Guide-CRISPRa

  GA106636G2, HEPH gRNA vector 2 in pCas-Guide-CRISPRa

  GA106636G3, HEPH gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130860, NM_001282141, NM_014799, NM_138737, NM_001367232, NM_001367233, NM_001367236, NM_001367238, NM_001367239, NM_001367240, NM_001367243, NR_159801, NM_001367234, NM_001367241, NM_001367242, NR_159800, NR_159802
• Synonyms: CPL
• Summary: This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]