Hephaestin (HEPH) Human Gene Knockout Kit (CRISPR)

CAT#: KN404175

HEPH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: HEPH
• Locus ID: 9843
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001130860, NM_001282141, NM_014799, NM_138737, NM_001367232, NM_001367233, NM_001367236, NM_001367238, NM_001367239, NM_001367240, NM_001367243, NR_159801, NM_001367234, NM_001367241, NM_001367242, NR_159800, NR_159802
• Synonyms: CPL
• Summary: This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]