Human KDM4C activation kit by CRISPRa

CAT#: GA108023

KDM4C CRISPRa kit - CRISPR gene activation of human lysine demethylase 4C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KDM4C
• Locus ID: 23081
• Kit Components:

  GA108023G1, KDM4C gRNA vector 1 in pCas-Guide-CRISPRa

  GA108023G2, KDM4C gRNA vector 2 in pCas-Guide-CRISPRa

  GA108023G3, KDM4C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146694, NM_001146695, NM_001146696, NM_001304339, NM_001304340, NM_001304341, NM_015061, NR_130707, NM_001353997, NM_001353998, NM_001353999, NM_001354000, NM_001354001, NR_148677, NR_148678, NR_148679, NR_148680
• Synonyms: bA146B14.1; GASC1; JHDM3C; JMJD2C; TDRD14C
• Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]