KDM4C Human Gene Knockout Kit (CRISPR)

CAT#: KN411182

KDM4C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.



KN2.0 knockout kit validation

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KN411182 is the updated version of KN211182.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol KDM4C
Locus ID 23081
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001146694, NM_001146695, NM_001146696, NM_001304339, NM_001304340, NM_001304341, NM_015061, NR_130707, NM_001353997, NM_001353998, NM_001353999, NM_001354000, NM_001354001, NR_148677, NR_148678, NR_148679, NR_148680
Synonyms bA146B14.1; GASC1; JHDM3C; JMJD2C; TDRD14C
Summary This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.