Human RACGAP1 activation kit by CRISPRa

CAT#: GA109257

RACGAP1 CRISPRa kit - CRISPR gene activation of human Rac GTPase activating protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RACGAP1
• Locus ID: 29127
• Kit Components:

  GA109257G1, RACGAP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109257G2, RACGAP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109257G3, RACGAP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001126103, NM_001126104, NM_001319999, NM_001320000, NM_001320001, NM_001320002, NM_001320003, NM_001320004, NM_001320005, NM_001320006, NM_001320007, NM_013277
• Synonyms: CYK4; HsCYK-4; ID-GAP; MgcRacGAP
• Summary: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]