Human Dermokine (DMKN) activation kit by CRISPRa

CAT#: GA114262

DMKN CRISPRa kit - CRISPR gene activation of human dermokine

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DMKN
• Locus ID: 93099
• Kit Components:

  GA114262G1, DMKN gRNA vector 1 in pCas-Guide-CRISPRa

  GA114262G2, DMKN gRNA vector 2 in pCas-Guide-CRISPRa

  GA114262G3, DMKN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001035516, NM_001126056, NM_001126057, NM_001126058, NM_001126059, NM_001126061, NM_001190347, NM_001190348, NM_001190349, NM_001308380, NM_001308383, NM_033317, NR_033746, NM_001352328, NM_001352329, NM_001352330, NM_001352331, NM_001352332, NR_147958, NR_147959
• Synonyms: UNQ729; ZD52F10
• Summary: This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]