Dermokine (DMKN) Human Gene Knockout Kit (CRISPR)

CAT#: KN411509

DMKN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: DMKN
• Locus ID: 93099
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001035516, NM_001126056, NM_001126057, NM_001126058, NM_001126059, NM_001126061, NM_001190347, NM_001190348, NM_001190349, NM_001308380, NM_001308383, NM_033317, NR_033746, NM_001352328, NM_001352329, NM_001352330, NM_001352331, NM_001352332, NR_147958, NR_147959
• Synonyms: UNQ729; ZD52F10
• Summary: This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]