c20orf72 (MGME1) Human Gene Knockout Kit (CRISPR)
CAT#: KN203886
MGME1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | MGME1 |
Locus ID | 92667 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001310338, NM_001310339, NM_052865, NM_001363738 |
Synonyms | bA504H3.4; C20orf72; DDK1; MTDPS11 |
Summary | The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN203886BN | MGME1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN203886LP | MGME1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN203886RB | MGME1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN403886 | MGME1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA114229 | MGME1 CRISPRa kit - CRISPR gene activation of human mitochondrial genome maintenance exonuclease 1 |
USD 1,290.00 |
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