c20orf72 (MGME1) Human Gene Knockout Kit (CRISPR)

CAT#: KN203886BN

MGME1 - human gene knockout kit via CRISPR, HDR mediated

SDS

HDR-mediated knockout kit validation

  See Other Versions

USD 1,290.00

4 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol MGME1
Locus ID 92667
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001310338, NM_001310339, NM_052865, NM_001363738
Synonyms bA504H3.4; C20orf72; DDK1; MTDPS11
Summary The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

Other Versions

SKU Description Size Price
KN203886 MGME1 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN203886LP MGME1 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN203886RB MGME1 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN403886 MGME1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

GA114229 MGME1 CRISPRa kit - CRISPR gene activation of human mitochondrial genome maintenance exonuclease 1
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.