LGR5 Human Gene Knockout Kit (CRISPR)
CAT#: KN212825BN
LGR5 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | LGR5 |
Locus ID | 8549 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001277226, NM_001277227, NM_003667, NR_110596 |
Synonyms | FEX; GPR49; GPR67; GRP49; HG38 |
Summary | The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN212825 | LGR5 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN212825LP | LGR5 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN212825RB | LGR5 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN412825 | LGR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA105663 | LGR5 CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing G protein-coupled receptor 5 |
USD 1,290.00 |
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